Lymphocyte Trafficking to Mucosal Tissues

Zamaneh Mikhak; William Winston Agace; Andrew D. Luster

doi:10.1016/B978-0-12-415847-4.00040-9

Lymphocyte Trafficking to Mucosal Tissues

Zamaneh Mikhak, William Winston Agace, Andrew D. Luster

Massachusetts General Hospital/Harvard Medical School

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Abstract

Lymphocytes are the key cells of the adaptive immune system that provide antigen-specific responses tailored to the context of antigen exposure. Through cytokine release and antibody production, lymphocytes orchestrate and amplify the recruitment and function of other immune cells and contribute to host defense against invading pathogens and the pathogenesis of many inflammatory diseases. Lymphocyte function is critically dependent on their ability to traffic into the correct anatomic locations at the appropriate times. This process is highly regulated and requires that lymphocytes interact with various homing molecules and respond to tightly regulated navigational cues.

Original language	English
Title of host publication	Mucosal Immunology
Editors	Jiri Mestecky, Warren Strober, Michael W. Russell, Hilde Cheroutre, Bart N. Lambrecht , Brian L. Kelsall
Volume	1
Publisher	Elsevier
Publication date	2015
Edition	4
Pages	805-830
ISBN (Print)	978-0-12-415847-4
DOIs	https://doi.org/10.1016/B978-0-12-415847-4.00040-9
Publication status	Published - 2015

Access to Document

10.1016/B978-0-12-415847-4.00040-9

OpenUrl availability

Full text

Cite this

@inbook{90bbc3dddf64419683f2b958649535b9,

title = "Lymphocyte Trafficking to Mucosal Tissues",

abstract = "Lymphocytes are the key cells of the adaptive immune system that provide antigen-specific responses tailored to the context of antigen exposure. Through cytokine release and antibody production, lymphocytes orchestrate and amplify the recruitment and function of other immune cells and contribute to host defense against invading pathogens and the pathogenesis of many inflammatory diseases. Lymphocyte function is critically dependent on their ability to traffic into the correct anatomic locations at the appropriate times. This process is highly regulated and requires that lymphocytes interact with various homing molecules and respond to tightly regulated navigational cues.",

author = "Zamaneh Mikhak and Agace, {William Winston} and Luster, {Andrew D.}",

year = "2015",

doi = "10.1016/B978-0-12-415847-4.00040-9",

language = "English",

isbn = "978-0-12-415847-4",

volume = "1",

pages = "805--830",

editor = "Mestecky, {Jiri } and Strober, {Warren } and Russell, {Michael W. } and Cheroutre, {Hilde } and {Lambrecht }, {Bart N. } and Kelsall, {Brian L. }",

booktitle = "Mucosal Immunology",

publisher = "Elsevier",

address = "United Kingdom",

edition = "4",

}

Lymphocyte Trafficking to Mucosal Tissues. / Mikhak, Zamaneh; Agace, William Winston; Luster, Andrew D.
Mucosal Immunology. ed. / Jiri Mestecky; Warren Strober; Michael W. Russell; Hilde Cheroutre; Bart N. Lambrecht ; Brian L. Kelsall. Vol. 1 4. ed. Elsevier, 2015. p. 805-830.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

TY - CHAP

T1 - Lymphocyte Trafficking to Mucosal Tissues

AU - Mikhak, Zamaneh

AU - Agace, William Winston

AU - Luster, Andrew D.

PY - 2015

Y1 - 2015

N2 - Lymphocytes are the key cells of the adaptive immune system that provide antigen-specific responses tailored to the context of antigen exposure. Through cytokine release and antibody production, lymphocytes orchestrate and amplify the recruitment and function of other immune cells and contribute to host defense against invading pathogens and the pathogenesis of many inflammatory diseases. Lymphocyte function is critically dependent on their ability to traffic into the correct anatomic locations at the appropriate times. This process is highly regulated and requires that lymphocytes interact with various homing molecules and respond to tightly regulated navigational cues.

AB - Lymphocytes are the key cells of the adaptive immune system that provide antigen-specific responses tailored to the context of antigen exposure. Through cytokine release and antibody production, lymphocytes orchestrate and amplify the recruitment and function of other immune cells and contribute to host defense against invading pathogens and the pathogenesis of many inflammatory diseases. Lymphocyte function is critically dependent on their ability to traffic into the correct anatomic locations at the appropriate times. This process is highly regulated and requires that lymphocytes interact with various homing molecules and respond to tightly regulated navigational cues.

U2 - 10.1016/B978-0-12-415847-4.00040-9

DO - 10.1016/B978-0-12-415847-4.00040-9

M3 - Book chapter

SN - 978-0-12-415847-4

VL - 1

SP - 805

EP - 830

BT - Mucosal Immunology

A2 - Mestecky, Jiri

A2 - Strober, Warren

A2 - Russell, Michael W.

A2 - Cheroutre, Hilde

A2 - Lambrecht , Bart N.

A2 - Kelsall, Brian L.

PB - Elsevier

ER -

Lymphocyte Trafficking to Mucosal Tissues

Abstract

Access to Document

OpenUrl availability

Fingerprint

Cite this