TY - JOUR
T1 - Luminescence from lanthanide(III) ions bound to the Glycocalyx of Chinese Hamster Ovary cells
AU - Arppe-Tabbara, Riikka
AU - Carro-Temboury, Miguel R
AU - Hempel, Casper
AU - Vosch, Tom
AU - Sørensen, Thomas Just
PY - 2018
Y1 - 2018
N2 - Lanthanide(III) ions bind to the glycocalyx of Chinese Hamster Ovary (CHO) cells and give rise to a unique luminescent fingerprint. Following direct excitation of terbium(III) or europium(III) ions in the visible part of the spectrum, we are able to collect emission spectra pixel-by-pixel in images of CHO cells. Following data analysis that removes the background signal, the fine structure of the europium(III) luminescence indicate that the lanthanide(III) ions are bound to a single structure of the CHO cell glycocalyx. This was deduced from the fact that the structure-sensitive emission spectrum of europium is unchanged throughout the investigatedsamples.
AB - Lanthanide(III) ions bind to the glycocalyx of Chinese Hamster Ovary (CHO) cells and give rise to a unique luminescent fingerprint. Following direct excitation of terbium(III) or europium(III) ions in the visible part of the spectrum, we are able to collect emission spectra pixel-by-pixel in images of CHO cells. Following data analysis that removes the background signal, the fine structure of the europium(III) luminescence indicate that the lanthanide(III) ions are bound to a single structure of the CHO cell glycocalyx. This was deduced from the fact that the structure-sensitive emission spectrum of europium is unchanged throughout the investigatedsamples.
U2 - 10.1002/chem.201802799
DO - 10.1002/chem.201802799
M3 - Journal article
C2 - 29939467
SN - 0947-6539
VL - 24
SP - 11885
EP - 11889
JO - Chemistry - A European Journal
JF - Chemistry - A European Journal
IS - 46
ER -