Luminescence from lanthanide(III) ions bound to the Glycocalyx of Chinese Hamster Ovary cells

Riikka Arppe-Tabbara, Miguel R Carro-Temboury, Casper Hempel*, Tom Vosch, Thomas Just Sørensen

*Corresponding author for this work

    Research output: Contribution to journalJournal articleResearchpeer-review

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    Abstract

    Lanthanide(III) ions bind to the glycocalyx of Chinese Hamster Ovary (CHO) cells and give rise to a unique luminescent fingerprint. Following direct excitation of terbium(III) or europium(III) ions in the visible part of the spectrum, we are able to collect emission spectra pixel-by-pixel in images of CHO cells. Following data analysis that removes the background signal, the fine structure of the europium(III) luminescence indicate that the lanthanide(III) ions are bound to a single structure of the CHO cell glycocalyx. This was deduced from the fact that the structure-sensitive emission spectrum of europium is unchanged throughout the investigated
    samples.
    Original languageEnglish
    JournalChemistry: A European Journal
    Volume24
    Issue number46
    Pages (from-to)11885-11889
    ISSN0947-6539
    DOIs
    Publication statusPublished - 2018

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