Low Physical Activity Level and Short Sleep Duration Are Associated with an Increased Cardio-Metabolic Risk Profile: A Longitudinal Study in 8-11 Year Old Danish Children

Mads F. Hjorth, Jean-Philippe Chaput, Camilla T. Damsgaard, Stine-Mathilde Dalskov, Rikke Andersen, Arne Astrup, Kim F. Michaelsen, Inge Tetens, Christian Ritz, Anders Sjodin

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Abstract

Background: As cardio-metabolic risk tracks from childhood to adulthood, a better understanding of the relationship between movement behaviors (physical activity, sedentary behavior and sleep) and cardio-metabolic risk in childhood may aid in preventing metabolic syndrome (MetS) in adulthood. Objective: To examine independent and combined cross-sectional and longitudinal associations between movement behaviors and the MetS score in 8-11 year old Danish children. Design: Physical activity, sedentary time and sleep duration (seven days and eight nights) were assessed by accelerometer and fat mass index (fat mass/height(2)) was assessed using Dual-energy X-ray absorptiometry. The MetS-score was based on z-scores of waist circumference, mean arterial blood pressure, homeostatic model assessment of insulin resistance, triglycerides and high density lipoprotein cholesterol. All measurements were taken at three time points separated by 100 days. Average of the three measurements was used as habitual behavior in the cross-sectional analysis and changes from first to third measurement was used in the longitudinal analysis. Results: 723 children were included. In the cross-sectional analysis, physical activity was negatively associated with the MetS-score (P
Original languageEnglish
Article numbere104677
JournalPLOS ONE
Volume9
Issue number8
Number of pages9
ISSN1932-6203
DOIs
Publication statusPublished - 2014

Keywords

  • adiposity level
  • habitual behavior
  • mean arterial blood pressure
  • movement behavior
  • physical activity level
  • sedentary behavior
  • short sleep duration
  • sleep duration
  • waist circumference
  • cardiometabolic disease heart disease, metabolic disease etiology
  • Primates Mammalia Vertebrata Chordata Animalia (Animals, Chordates, Humans, Mammals, Primates, Vertebrates) - Hominidae [86215] human common child, preadolescent child Danish
  • high-density lipoprotein cholesterol
  • triglycerides
  • 05500, Social biology and human ecology
  • 07002, Behavioral biology - General and comparative behavior
  • 07004, Behavioral biology - Human behavior
  • 10066, Biochemistry studies - Lipids
  • 10067, Biochemistry studies - Sterols and steroids
  • 13002, Metabolism - General metabolism and metabolic pathways
  • 13020, Metabolism - Metabolic disorders
  • 14506, Cardiovascular system - Heart pathology
  • 25000, Pediatrics
  • 37001, Public health - General and miscellaneous
  • Human Medicine, Medical Sciences
  • accelerometer laboratory equipment
  • dual-energy X-ray absorptiometry laboratory techniques, spectrum analysis techniques
  • fat mass index clinical techniques, diagnostic techniques
  • homeostatic model assessment of insulin resistance clinical techniques, diagnostic techniques
  • metabolic syndrome score MetS score clinical techniques, diagnostic techniques
  • Behavior
  • Cardiovascular Medicine
  • Metabolism
  • Pediatrics
  • Population Studies
  • MULTIDISCIPLINARY
  • POPULATION-BASED SAMPLE
  • SEDENTARY BEHAVIOR
  • INSULIN-RESISTANCE
  • OBESE CHILDREN
  • CARDIORESPIRATORY FITNESS
  • INTERNATIONAL SURVEY
  • QUEBEC CHILDREN
  • BLOOD-PRESSURE
  • LIPID PROFILE
  • ADOLESCENTS

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