Low dose effects and non-monotonic dose responses for endocrine active chemicals: Science to practice workshop: Workshop summary

Research output: Contribution to journalJournal article – Annual report year: 2013Researchpeer-review

  • Author: Beausoleil, Claire

    ANSES - French Agency for Food, Environmental and Occupational Health & Safety, France

  • Author: Ormsby, Jean-Nicolas

    ANSES - French Agency for Food, Environmental and Occupational Health & Safety, France

  • Author: Gies, Andreas

    German Environment Agency, Germany

  • Author: Hass, Ulla

    Division of Toxicology and Risk Assessment, National Food Institute, Technical University of Denmark, Kemitorvet, 2800, Kgs. Lyngby, Denmark

  • Author: Heindel, Jerrold J.

    US National Institute of Health, United States

  • Author: Holmer, Marie Louise

    The Danish Environmental Protection Agency, Denmark

  • Author: Nielsen, Pia Juul

    The Danish Environmental Protection Agency, Denmark

  • Author: Munn, Sharon

    European Commission Joint Research Centre Institute, Italy

  • Author: Schoenfelder, Gilbert

    Charité – Universitätsmedizin Berlin, Germany

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A workshop was held in Berlin September 12–14th 2012 to assess the state of the science of the data supporting low dose effects and non-monotonic dose responses (“low dose hypothesis”) for chemicals with endocrine activity (endocrine disrupting chemicals or EDCs). This workshop consisted of lectures to present the current state of the science of EDC action and also the risk assessment process. These lectures were followed by breakout sessions to integrate scientists from various backgrounds to discuss in an open and unbiased manner the data supporting the “low dose hypothesis”. While no consensus was reached the robust discussions were helpful to inform both basic scientists and risk assessors on all the issues. There were a number of important ideas developed to help continue the discussion and improve communication over the next few years.
Original languageEnglish
JournalChemosphere
Volume93
Issue number6
Pages (from-to)847-856
ISSN0045-6535
DOIs
Publication statusPublished - 2013
CitationsWeb of Science® Times Cited: No match on DOI

    Research areas

  • Low dose effects, Non-monotonic dose responses, Endocrine disruptors, Risk assessment

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