Long-term exposure to wind turbine noise and redemption of antihypertensive medication: A nationwide cohort study

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Long-term exposure to wind turbine noise and redemption of antihypertensive medication: A nationwide cohort study. / Poulsen, Aslak Harbo; Raaschou-Nielsen, Ole; Pena Diaz, Alfredo; Hahmann, Andrea N.; Nordsborg, Rikke Baastrup; Ketzel, Matthias; Brandt, Jørgen; Sørensen, Mette.

In: Environment International, Vol. 121, No. Part 1, 2018, p. 207-215.

Research output: Contribution to journalJournal article – Annual report year: 2018Researchpeer-review

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Poulsen, Aslak Harbo ; Raaschou-Nielsen, Ole ; Pena Diaz, Alfredo ; Hahmann, Andrea N. ; Nordsborg, Rikke Baastrup ; Ketzel, Matthias ; Brandt, Jørgen ; Sørensen, Mette. / Long-term exposure to wind turbine noise and redemption of antihypertensive medication: A nationwide cohort study. In: Environment International. 2018 ; Vol. 121, No. Part 1. pp. 207-215.

Bibtex

@article{7fb061e271a644b182db9bc12368c70b,
title = "Long-term exposure to wind turbine noise and redemption of antihypertensive medication: A nationwide cohort study",
abstract = "Noise from wind turbines (WTs) has been reported more annoying than traffic noise at similar levels, and concerns have been raised about whether WT noise (WTN) can increase risk for cardiovascular disease. We aimed to investigate if long-term exposure to WTN increases risk for hypertension, estimated as redemption of prescriptions for antihypertensive drugs. We identified all Danish dwellings within a radius of 20 WT heights from a WT and 25{\%} randomly selected dwellings within 20-40 WT heights radius. Using data on WT type and hourly wind conditions at each WT, we estimated hourly outdoor (10-10,000 Hz) and low frequency (LF: 10-160 Hz) indoor WTN for all dwellings, and aggregated it as long-term nighttime running means. From nationwide registries, we identified 535,675 persons age 25-85 years living in these dwellings for >1 year from 1996 to 2013, of whom 83,729 fulfilled our case definition of redeeming ≥2 prescriptions and ≥180 defined daily doses of antihypertensive drugs within a year. Data were analyzed using Poisson regression according to categories of WTN exposure and adjustment for individual and area-level covariates. We found no associations between 5-year mean exposure to WTN during night and redemption of antihypertensives, with hazard ratios (HR) of 0.91 (95{\%} confidence intervals (CI): 0.78-1.06) for outdoor WTN ≥ 42 dB(A) and of 1.06 (CI: 0.83-1.35) for indoor LF WTN ≥ 15 dB(A) when compared to the reference WTN levels (",
keywords = "Antihypertensives, Epidemiology, Hypertension, Prescription, Prospective, Wind turbine noise",
author = "Poulsen, {Aslak Harbo} and Ole Raaschou-Nielsen and {Pena Diaz}, Alfredo and Hahmann, {Andrea N.} and Nordsborg, {Rikke Baastrup} and Matthias Ketzel and J{\o}rgen Brandt and Mette S{\o}rensen",
year = "2018",
doi = "10.1016/j.envint.2018.08.054",
language = "English",
volume = "121",
pages = "207--215",
journal = "Environment International",
issn = "0160-4120",
publisher = "Pergamon Press",
number = "Part 1",

}

RIS

TY - JOUR

T1 - Long-term exposure to wind turbine noise and redemption of antihypertensive medication: A nationwide cohort study

AU - Poulsen, Aslak Harbo

AU - Raaschou-Nielsen, Ole

AU - Pena Diaz, Alfredo

AU - Hahmann, Andrea N.

AU - Nordsborg, Rikke Baastrup

AU - Ketzel, Matthias

AU - Brandt, Jørgen

AU - Sørensen, Mette

PY - 2018

Y1 - 2018

N2 - Noise from wind turbines (WTs) has been reported more annoying than traffic noise at similar levels, and concerns have been raised about whether WT noise (WTN) can increase risk for cardiovascular disease. We aimed to investigate if long-term exposure to WTN increases risk for hypertension, estimated as redemption of prescriptions for antihypertensive drugs. We identified all Danish dwellings within a radius of 20 WT heights from a WT and 25% randomly selected dwellings within 20-40 WT heights radius. Using data on WT type and hourly wind conditions at each WT, we estimated hourly outdoor (10-10,000 Hz) and low frequency (LF: 10-160 Hz) indoor WTN for all dwellings, and aggregated it as long-term nighttime running means. From nationwide registries, we identified 535,675 persons age 25-85 years living in these dwellings for >1 year from 1996 to 2013, of whom 83,729 fulfilled our case definition of redeeming ≥2 prescriptions and ≥180 defined daily doses of antihypertensive drugs within a year. Data were analyzed using Poisson regression according to categories of WTN exposure and adjustment for individual and area-level covariates. We found no associations between 5-year mean exposure to WTN during night and redemption of antihypertensives, with hazard ratios (HR) of 0.91 (95% confidence intervals (CI): 0.78-1.06) for outdoor WTN ≥ 42 dB(A) and of 1.06 (CI: 0.83-1.35) for indoor LF WTN ≥ 15 dB(A) when compared to the reference WTN levels (

AB - Noise from wind turbines (WTs) has been reported more annoying than traffic noise at similar levels, and concerns have been raised about whether WT noise (WTN) can increase risk for cardiovascular disease. We aimed to investigate if long-term exposure to WTN increases risk for hypertension, estimated as redemption of prescriptions for antihypertensive drugs. We identified all Danish dwellings within a radius of 20 WT heights from a WT and 25% randomly selected dwellings within 20-40 WT heights radius. Using data on WT type and hourly wind conditions at each WT, we estimated hourly outdoor (10-10,000 Hz) and low frequency (LF: 10-160 Hz) indoor WTN for all dwellings, and aggregated it as long-term nighttime running means. From nationwide registries, we identified 535,675 persons age 25-85 years living in these dwellings for >1 year from 1996 to 2013, of whom 83,729 fulfilled our case definition of redeeming ≥2 prescriptions and ≥180 defined daily doses of antihypertensive drugs within a year. Data were analyzed using Poisson regression according to categories of WTN exposure and adjustment for individual and area-level covariates. We found no associations between 5-year mean exposure to WTN during night and redemption of antihypertensives, with hazard ratios (HR) of 0.91 (95% confidence intervals (CI): 0.78-1.06) for outdoor WTN ≥ 42 dB(A) and of 1.06 (CI: 0.83-1.35) for indoor LF WTN ≥ 15 dB(A) when compared to the reference WTN levels (

KW - Antihypertensives

KW - Epidemiology

KW - Hypertension

KW - Prescription

KW - Prospective

KW - Wind turbine noise

U2 - 10.1016/j.envint.2018.08.054

DO - 10.1016/j.envint.2018.08.054

M3 - Journal article

VL - 121

SP - 207

EP - 215

JO - Environment International

JF - Environment International

SN - 0160-4120

IS - Part 1

ER -