Light-Induced Local Heating for Thermophoretic Manipulation of DNA in Polymer Micro- and Nanochannels

Lasse Højlund Thamdrup; Niels Bent Larsen; Anders Kristensen

doi:10.1021/nl903190q

Light-Induced Local Heating for Thermophoretic Manipulation of DNA in Polymer Micro- and Nanochannels

Lasse Højlund Thamdrup, Niels Bent Larsen, Anders Kristensen

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

We present a method for making polymer chips with a narrow-band near-infrared absorber layer that enables light-induced local heating of liquids inside fluidic micro- and nanochannels fabricated by thermal imprint in polymethyl methacrylate. We have characterized the resulting liquid temperature profiles in microchannels using the temperature dependent fluorescence of the complex [Ru(bpy)3]2+. We demonstrate thermophoretic manipulation of individual YOYO-1 stained T4 DNA molecules inside micro- and nanochannels.

Original language	English
Journal	Nano Letters
Volume	10
Issue number	3
Pages (from-to)	826-832
ISSN	1530-6984
DOIs	https://doi.org/10.1021/nl903190q
Publication status	Published - 2010

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http://pubs.acs.org/doi/abs/10.1021/nl903190q

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title = "Light-Induced Local Heating for Thermophoretic Manipulation of DNA in Polymer Micro- and Nanochannels",

abstract = "We present a method for making polymer chips with a narrow-band near-infrared absorber layer that enables light-induced local heating of liquids inside fluidic micro- and nanochannels fabricated by thermal imprint in polymethyl methacrylate. We have characterized the resulting liquid temperature profiles in microchannels using the temperature dependent fluorescence of the complex [Ru(bpy)3]2+. We demonstrate thermophoretic manipulation of individual YOYO-1 stained T4 DNA molecules inside micro- and nanochannels.",

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journal = "Nano Letters",

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AU - Thamdrup, Lasse Højlund

AU - Larsen, Niels Bent

AU - Kristensen, Anders

PY - 2010

Y1 - 2010

N2 - We present a method for making polymer chips with a narrow-band near-infrared absorber layer that enables light-induced local heating of liquids inside fluidic micro- and nanochannels fabricated by thermal imprint in polymethyl methacrylate. We have characterized the resulting liquid temperature profiles in microchannels using the temperature dependent fluorescence of the complex [Ru(bpy)3]2+. We demonstrate thermophoretic manipulation of individual YOYO-1 stained T4 DNA molecules inside micro- and nanochannels.

AB - We present a method for making polymer chips with a narrow-band near-infrared absorber layer that enables light-induced local heating of liquids inside fluidic micro- and nanochannels fabricated by thermal imprint in polymethyl methacrylate. We have characterized the resulting liquid temperature profiles in microchannels using the temperature dependent fluorescence of the complex [Ru(bpy)3]2+. We demonstrate thermophoretic manipulation of individual YOYO-1 stained T4 DNA molecules inside micro- and nanochannels.

U2 - 10.1021/nl903190q

DO - 10.1021/nl903190q

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SN - 1530-6984

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JO - Nano Letters

JF - Nano Letters

IS - 3

ER -

Light-Induced Local Heating for Thermophoretic Manipulation of DNA in Polymer Micro- and Nanochannels

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