Abstract
We show that the selective enzymatic synthesis of specific cyclodextrins can be modulated using light. We use enzyme-mediated dynamic combinatorial chemistry to generate a mixture of interconverting linear and cyclic α-1,4-glucans, and employ an azobenzene photoswitch as a template. Using UV or blue light to switch between photostationary states with different azobenzene cis/trans isomeric ratios, we can promote the out-of-equilibrium assembly of either α-cyclodextrin or β-cyclodextrin.
Original language | English |
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Journal | Chemical Communications |
Volume | 55 |
Issue number | 100 |
Pages (from-to) | 15037-15040 |
ISSN | 1359-7345 |
DOIs | |
Publication status | Published - 2019 |