Abstract
| Original language | English |
|---|---|
| Journal | Chemical Communications |
| Volume | 55 |
| Issue number | 100 |
| Pages (from-to) | 15037-15040 |
| Number of pages | 4 |
| ISSN | 1359-7345 |
| DOIs | |
| Publication status | Published - 2019 |
Cite this
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Light-controlled out-of-equilibrium assembly of cyclodextrins in an enzyme-mediated dynamic system. / Larsen, Dennis; Bjerre, Philip M.; Beeren, Sophie R.
In: Chemical Communications, Vol. 55, No. 100, 2019, p. 15037-15040.Research output: Contribution to journal › Journal article › Research › peer-review
TY - JOUR
T1 - Light-controlled out-of-equilibrium assembly of cyclodextrins in an enzyme-mediated dynamic system
AU - Larsen, Dennis
AU - Bjerre, Philip M.
AU - Beeren, Sophie R.
PY - 2019
Y1 - 2019
N2 - We show that the selective enzymatic synthesis of specific cyclodextrins can be modulated using light. We use enzyme-mediated dynamic combinatorial chemistry to generate a mixture of interconverting linear and cyclic α-1,4-glucans, and employ an azobenzene photoswitch as a template. Using UV or blue light to switch between photostationary states with different azobenzene cis/trans isomeric ratios, we can promote the out-of-equilibrium assembly of either α-cyclodextrin or β-cyclodextrin.
AB - We show that the selective enzymatic synthesis of specific cyclodextrins can be modulated using light. We use enzyme-mediated dynamic combinatorial chemistry to generate a mixture of interconverting linear and cyclic α-1,4-glucans, and employ an azobenzene photoswitch as a template. Using UV or blue light to switch between photostationary states with different azobenzene cis/trans isomeric ratios, we can promote the out-of-equilibrium assembly of either α-cyclodextrin or β-cyclodextrin.
U2 - 10.1039/c9cc08452e
DO - 10.1039/c9cc08452e
M3 - Journal article
C2 - 31782430
VL - 55
SP - 15037
EP - 15040
JO - Chemical Communications
JF - Chemical Communications
SN - 1359-7345
IS - 100
ER -