Legacy data sharing to improve drug safety assessment: the eTOX project

Ferran Sanz, François Pognan, Thomas Steger-Hartmann, Carlos Díaz, eTOX, Montserrat Cases, Manuel Pastor, Philippe Marc, Joerg Wichard, Katharine Briggs, David K Watson, Thomas Kleinöder, Chihae Yang, Alexander Amberg, Maria Beaumont, Anthony J Brookes, Søren Brunak, Mark T. D. Cronin, Gerhard F. Ecker, Sylvia EscherNigel Greene, Antonio Guzmán, Anne Hersey, Pascale Jacques, Lieve Lammens, Jordi Mestres, Wolfgang Muster, Helle Northeved, Marc Pinches, Javier Saiz, Nicolas Sajot, Alfonso Valencia, Johan van der Lei, Nico P E Vermeulen, Esther Vock, Gerhard Wolber, Ismael Zamora

    Research output: Contribution to journalJournal articleCommunication

    Abstract

    The sharing of legacy preclinical safety data among pharmaceutical companies and its integration with other information sources offers unprecedented opportunities to improve the early assessment of drug safety. Here, we discuss the experience of the eTOX project, which was established through the Innovative Medicines Initiative to explore this possibility.
    Original languageEnglish
    JournalNature Reviews. Drug Discovery
    Volume16
    Pages (from-to)811-812
    ISSN1474-1784
    DOIs
    Publication statusPublished - 2017

    Cite this

    Sanz, F., Pognan, F., Steger-Hartmann, T., Díaz, C., eTOX, Cases, M., Pastor, M., Marc, P., Wichard, J., Briggs, K., Watson, D. K., Kleinöder, T., Yang, C., Amberg, A., Beaumont, M., Brookes, A. J., Brunak, S., Cronin, M. T. D., Ecker, G. F., ... Zamora, I. (2017). Legacy data sharing to improve drug safety assessment: the eTOX project. Nature Reviews. Drug Discovery, 16, 811-812. https://doi.org/10.1038/nrd.2017.177