Legacy data sharing to improve drug safety assessment: the eTOX project

Ferran Sanz, François Pognan, Thomas Steger-Hartmann, Carlos Díaz, eTOX, Montserrat Cases, Manuel Pastor, Philippe Marc, Joerg Wichard, Katharine Briggs, David K Watson, Thomas Kleinöder, Chihae Yang, Alexander Amberg, Maria Beaumont, Anthony J Brookes, Søren Brunak, Mark T. D. Cronin, Gerhard F. Ecker, Sylvia EscherNigel Greene, Antonio Guzmán, Anne Hersey, Pascale Jacques, Lieve Lammens, Jordi Mestres, Wolfgang Muster, Helle Northeved, Marc Pinches, Javier Saiz, Nicolas Sajot, Alfonso Valencia, Johan van der Lei, Nico P E Vermeulen, Esther Vock, Gerhard Wolber, Ismael Zamora

    Research output: Contribution to journalJournal articleCommunication


    The sharing of legacy preclinical safety data among pharmaceutical companies and its integration with other information sources offers unprecedented opportunities to improve the early assessment of drug safety. Here, we discuss the experience of the eTOX project, which was established through the Innovative Medicines Initiative to explore this possibility.
    Original languageEnglish
    JournalNature Reviews. Drug Discovery
    Pages (from-to)811-812
    Publication statusPublished - 2017


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