Leaky Opto-Electrical Neural Probe for Optical Stimulation and Electrochemical Detection of Dopamine Exocytosis

Shashank Vasudevan, Janko Kajtez, Arto Heiskanen, Jenny Emnéus, Stephan Sylvest Keller*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Abstract

This paper reports on the fabrication and characterization of leaky opto-electrical neural probes for optical stimulation and real time electrochemical detection of dopamine exocytosis from optogenetically modified neural stem cells. Indentations were introduced in a SU-8 waveguide structure, patterned directly on the probe shank, to allow light to leak over a large area. Pyrolytic carbon electrodes fabricated on both sides of the leaky waveguide allow for real time detection of dopamine. The electrochemical characterization of the pyrolytic carbon demonstrates excellent conductivity and suitability for dopamine detection.
Original languageEnglish
Title of host publicationProceedings of the 2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS)
Number of pages4
PublisherIEEE
Publication date2020
Pages388-391
Article number9056270
ISBN (Electronic)978-1-7281-3581-6
DOIs
Publication statusPublished - 2020
Event2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems - Vancouver, Canada
Duration: 18 Jan 202020 Jan 2020

Conference

Conference2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems
CountryCanada
CityVancouver
Period18/01/202020/01/2020
SeriesInternational Conference on Micro Electro Mechanical Systems
ISSN1084-6999

Keywords

  • Optical neural probe
  • Leaky waveguide
  • Optogenetics
  • Electrochemistry
  • Dopamine detection

Cite this

Vasudevan, S., Kajtez, J., Heiskanen, A., Emnéus, J., & Keller, S. S. (2020). Leaky Opto-Electrical Neural Probe for Optical Stimulation and Electrochemical Detection of Dopamine Exocytosis. In Proceedings of the 2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS) (pp. 388-391). [9056270] IEEE. International Conference on Micro Electro Mechanical Systems https://doi.org/10.1109/mems46641.2020.9056270