Abstract
This paper reports on the fabrication and characterization of leaky opto-electrical neural probes for optical stimulation and real time electrochemical detection of dopamine exocytosis from optogenetically modified neural stem cells. Indentations were introduced in a SU-8 waveguide structure, patterned directly on the probe shank, to allow light to leak over a large area. Pyrolytic carbon electrodes fabricated on both sides of the leaky waveguide allow for real time detection of dopamine. The electrochemical characterization of the pyrolytic carbon demonstrates excellent conductivity and suitability for dopamine detection.
Original language | English |
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Title of host publication | Proceedings of the 2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems (MEMS) |
Number of pages | 4 |
Publisher | IEEE |
Publication date | 2020 |
Pages | 388-391 |
Article number | 9056270 |
ISBN (Electronic) | 978-1-7281-3581-6 |
DOIs | |
Publication status | Published - 2020 |
Event | 2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems - Vancouver, Canada Duration: 18 Jan 2020 → 20 Jan 2020 Conference number: 33 https://ieeexplore.ieee.org/xpl/conhome/9039791/proceeding |
Conference
Conference | 2020 IEEE 33rd International Conference on Micro Electro Mechanical Systems |
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Number | 33 |
Country/Territory | Canada |
City | Vancouver |
Period | 18/01/2020 → 20/01/2020 |
Internet address |
Series | International Conference on Micro Electro Mechanical Systems |
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ISSN | 1084-6999 |
Keywords
- Optical neural probe
- Leaky waveguide
- Optogenetics
- Electrochemistry
- Dopamine detection