Large-scale, Lithography-free Production of Transparent Nanostructured Surface for Dual-functional Electrochemical and SERS Sensing

Kuldeep Sanger, Onur Durucan, Kaiyu Wu, Anil Haraksingh Thilsted, Arto R Heiskanen, Tomas Rindzevicius, Michael Stenbæk Schmidt, Kinga Zor, Anja Boisen

Research output: Contribution to journalJournal articleResearchpeer-review

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Abstract

In this work, we present a dual-functional sensor that can perform surface-enhanced Raman spectroscopy (SERS) based identification and electrochemical (EC) quantification of analytes in liquid samples. A lithography-free reactive ion etching process was utilized to obtain nanostructures of high aspect ratios distributed homogeneously on a 4-inch fused silica wafer. The sensor was made up of three-electrode array, obtained by subsequent e-beam evaporation of Au on nanostructures in selected areas through a shadow mask. The SERS performance was evaluated through surface-averaged enhancement factor (EF), which was ~6.2 x 105, and spatial uniformity of EF, which was ~13% in terms of relative standard deviation. Excellent electrochemical performance and reproducibility were revealed by recording cyclic voltammograms. On nanostructured electrodes, paracetamol (PAR) showed an improved quasi-reversible behavior with decrease in peak potential separation (∆Ep ~90mV) and higher peak currents (Ipa/Ipc ~1), comparing to planar electrodes (∆Ep ~560mV). The oxidation potential of PAR was also lowered by ~80 mV on nanostructured electrodes. To illustrate dual-functional sensing, quantitative evaluation of PAR ranging from 30 µM to 3 mM was realized through EC detection, and presence of PAR was verified by its SERS fingerprint.
Original languageEnglish
JournalACS Sensors
Volume2
Issue number12
Pages (from-to)1869–1875
ISSN2379-3694
DOIs
Publication statusPublished - 2017

Keywords

  • Lithography-free
  • Dual-functional
  • Electrochemical
  • SERS
  • Paracetamol

Cite this

@article{1f1b1917ea194605ab5aecd314c192dc,
title = "Large-scale, Lithography-free Production of Transparent Nanostructured Surface for Dual-functional Electrochemical and SERS Sensing",
abstract = "In this work, we present a dual-functional sensor that can perform surface-enhanced Raman spectroscopy (SERS) based identification and electrochemical (EC) quantification of analytes in liquid samples. A lithography-free reactive ion etching process was utilized to obtain nanostructures of high aspect ratios distributed homogeneously on a 4-inch fused silica wafer. The sensor was made up of three-electrode array, obtained by subsequent e-beam evaporation of Au on nanostructures in selected areas through a shadow mask. The SERS performance was evaluated through surface-averaged enhancement factor (EF), which was ~6.2 x 105, and spatial uniformity of EF, which was ~13{\%} in terms of relative standard deviation. Excellent electrochemical performance and reproducibility were revealed by recording cyclic voltammograms. On nanostructured electrodes, paracetamol (PAR) showed an improved quasi-reversible behavior with decrease in peak potential separation (∆Ep ~90mV) and higher peak currents (Ipa/Ipc ~1), comparing to planar electrodes (∆Ep ~560mV). The oxidation potential of PAR was also lowered by ~80 mV on nanostructured electrodes. To illustrate dual-functional sensing, quantitative evaluation of PAR ranging from 30 µM to 3 mM was realized through EC detection, and presence of PAR was verified by its SERS fingerprint.",
keywords = "Lithography-free, Dual-functional, Electrochemical, SERS, Paracetamol",
author = "Kuldeep Sanger and Onur Durucan and Kaiyu Wu and Thilsted, {Anil Haraksingh} and Heiskanen, {Arto R} and Tomas Rindzevicius and Schmidt, {Michael Stenb{\ae}k} and Kinga Zor and Anja Boisen",
year = "2017",
doi = "10.1021/acssensors.7b00783",
language = "English",
volume = "2",
pages = "1869–1875",
journal = "ACS Sensors",
issn = "2379-3694",
publisher = "American Chemical Society",
number = "12",

}

Large-scale, Lithography-free Production of Transparent Nanostructured Surface for Dual-functional Electrochemical and SERS Sensing. / Sanger, Kuldeep; Durucan, Onur; Wu, Kaiyu; Thilsted, Anil Haraksingh; Heiskanen, Arto R; Rindzevicius, Tomas; Schmidt, Michael Stenbæk; Zor, Kinga; Boisen, Anja.

In: ACS Sensors, Vol. 2, No. 12, 2017, p. 1869–1875.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Large-scale, Lithography-free Production of Transparent Nanostructured Surface for Dual-functional Electrochemical and SERS Sensing

AU - Sanger, Kuldeep

AU - Durucan, Onur

AU - Wu, Kaiyu

AU - Thilsted, Anil Haraksingh

AU - Heiskanen, Arto R

AU - Rindzevicius, Tomas

AU - Schmidt, Michael Stenbæk

AU - Zor, Kinga

AU - Boisen, Anja

PY - 2017

Y1 - 2017

N2 - In this work, we present a dual-functional sensor that can perform surface-enhanced Raman spectroscopy (SERS) based identification and electrochemical (EC) quantification of analytes in liquid samples. A lithography-free reactive ion etching process was utilized to obtain nanostructures of high aspect ratios distributed homogeneously on a 4-inch fused silica wafer. The sensor was made up of three-electrode array, obtained by subsequent e-beam evaporation of Au on nanostructures in selected areas through a shadow mask. The SERS performance was evaluated through surface-averaged enhancement factor (EF), which was ~6.2 x 105, and spatial uniformity of EF, which was ~13% in terms of relative standard deviation. Excellent electrochemical performance and reproducibility were revealed by recording cyclic voltammograms. On nanostructured electrodes, paracetamol (PAR) showed an improved quasi-reversible behavior with decrease in peak potential separation (∆Ep ~90mV) and higher peak currents (Ipa/Ipc ~1), comparing to planar electrodes (∆Ep ~560mV). The oxidation potential of PAR was also lowered by ~80 mV on nanostructured electrodes. To illustrate dual-functional sensing, quantitative evaluation of PAR ranging from 30 µM to 3 mM was realized through EC detection, and presence of PAR was verified by its SERS fingerprint.

AB - In this work, we present a dual-functional sensor that can perform surface-enhanced Raman spectroscopy (SERS) based identification and electrochemical (EC) quantification of analytes in liquid samples. A lithography-free reactive ion etching process was utilized to obtain nanostructures of high aspect ratios distributed homogeneously on a 4-inch fused silica wafer. The sensor was made up of three-electrode array, obtained by subsequent e-beam evaporation of Au on nanostructures in selected areas through a shadow mask. The SERS performance was evaluated through surface-averaged enhancement factor (EF), which was ~6.2 x 105, and spatial uniformity of EF, which was ~13% in terms of relative standard deviation. Excellent electrochemical performance and reproducibility were revealed by recording cyclic voltammograms. On nanostructured electrodes, paracetamol (PAR) showed an improved quasi-reversible behavior with decrease in peak potential separation (∆Ep ~90mV) and higher peak currents (Ipa/Ipc ~1), comparing to planar electrodes (∆Ep ~560mV). The oxidation potential of PAR was also lowered by ~80 mV on nanostructured electrodes. To illustrate dual-functional sensing, quantitative evaluation of PAR ranging from 30 µM to 3 mM was realized through EC detection, and presence of PAR was verified by its SERS fingerprint.

KW - Lithography-free

KW - Dual-functional

KW - Electrochemical

KW - SERS

KW - Paracetamol

U2 - 10.1021/acssensors.7b00783

DO - 10.1021/acssensors.7b00783

M3 - Journal article

VL - 2

SP - 1869

EP - 1875

JO - ACS Sensors

JF - ACS Sensors

SN - 2379-3694

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ER -