Lactococcus lactis is diploid

Ole Michelsen (Invited author), Peter Ruhdal Jensen (Invited author)

    Research output: Contribution to conferencePaperResearch

    Abstract

    As part of a collaboration with Danish Dairy Research Foundation we are interested in the DNA replication of Lactococcus lactis. For that we implemented flowcytometric analysis for these studies. The L. lactis does not respond to inhibition by rifampicin by finishing ongoing replication forks. We therefore turned to slow growing cultures in order to obtain information about the DNA replication in the cell cycle. From these studies we have obtained evidence that suggest that slow growing L. lactis are born with two chromosomes in contrast to other studied bacteria, which are born with one chromosome. This unexpected result has been confirmed by radioactive labelling of slow growing cultures of Lactococcus lactis, which also showed the presence of two chromosomes. We therefore conclude that Lactococcus lactis is the first diploid bacterium found.
    Original languageEnglish
    Publication date2005
    Publication statusPublished - 2005
    EventDanish Food Science 2005 : From molecule to man - DTU
    Duration: 1 Jan 2005 → …

    Conference

    ConferenceDanish Food Science 2005 : From molecule to man
    CityDTU
    Period01/01/2005 → …

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