Investigation of the Thermostability of Bovine Submaxillary Mucin (BSM) and its Impact on Lubrication

Jan Busk Madsen, Kirsi I. Pakkanen, Seunghwan Lee, Yang Dan

    Research output: Contribution to journalConference articleResearchpeer-review

    410 Downloads (Pure)

    Abstract

    Bovine Submaxillary Mucin (BSM) generates thin film layers via spontaneous adsorption onto hydrophobic surfaces such as Poly(dimethylsiloxane) (PDMS) and High Density Polyethylene (HDPE). A characteristic feature of mucin is its tribological- or lubricating properties. Circular dichroismspectroscopyrevealed that BSM is thermally stable over a wide range of temperatures (5–85°C) in its conformation, and Pin-on-Disk tribometry at low speeds showed negligible influence on lubricating properties. Employing the Mini Traction Machine, BSM was found to retain comparable lubricating properties after heating to 80°C and subsequent cooling. Random coiled secondary- and lack of tertiary structure in BSM is believed to contribute to the heat tolerance observed with regards to its conformational and lubrication properties.
    Original languageEnglish
    JournalA P C B E E Procedia
    Volume7
    Pages (from-to)21-26
    ISSN2212-6708
    DOIs
    Publication statusPublished - 2013
    Event3rd International Conference on Biomedical Engineering and Technology (ICBET 2013) - Copenhagen, Denmark
    Duration: 19 May 201320 May 2013
    Conference number: 3

    Conference

    Conference3rd International Conference on Biomedical Engineering and Technology (ICBET 2013)
    Number3
    Country/TerritoryDenmark
    CityCopenhagen
    Period19/05/201320/05/2013

    Bibliographical note

    Asia-Pacific Chemical, Biological & Environmental Engineering Society

    Keywords

    • Bovine Submaxillary Mucin
    • Biolubrication
    • Surface Coating
    • Biotribology

    Fingerprint

    Dive into the research topics of 'Investigation of the Thermostability of Bovine Submaxillary Mucin (BSM) and its Impact on Lubrication'. Together they form a unique fingerprint.

    Cite this