Investigation of the Thermostability of Bovine Submaxillary Mucin (BSM) and its Impact on Lubrication

Jan Busk Madsen, Kirsi I. Pakkanen, Seunghwan Lee, Yang Dan

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Bovine Submaxillary Mucin (BSM) generates thin film layers via spontaneous adsorption onto hydrophobic surfaces such as Poly(dimethylsiloxane) (PDMS) and High Density Polyethylene (HDPE). A characteristic feature of mucin is its tribological- or lubricating properties. Circular dichroismspectroscopyrevealed that BSM is thermally stable over a wide range of temperatures (5–85°C) in its conformation, and Pin-on-Disk tribometry at low speeds showed negligible influence on lubricating properties. Employing the Mini Traction Machine, BSM was found to retain comparable lubricating properties after heating to 80°C and subsequent cooling. Random coiled secondary- and lack of tertiary structure in BSM is believed to contribute to the heat tolerance observed with regards to its conformational and lubrication properties.
Original languageEnglish
JournalA P C B E E Procedia
Pages (from-to)21-26
Publication statusPublished - 2013
Event3rd International Conference on Biomedical Engineering and Technology (ICBET 2013) - Copenhagen, Denmark
Duration: 19 May 201320 May 2013
Conference number: 3


Conference3rd International Conference on Biomedical Engineering and Technology (ICBET 2013)

Bibliographical note

Asia-Pacific Chemical, Biological & Environmental Engineering Society


  • Bovine Submaxillary Mucin
  • Biolubrication
  • Surface Coating
  • Biotribology

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