INTRODUCTION: Immune Relevant Animal Models: Opportunities and Challenges

Gregers Jungersen, Jorge Piedrahita

Research output: Contribution to journalJournal articleCommunication

Abstract

Valid interpretation of preclinical animal models in immunology-related clinical challenges is important to solve outstanding clinical needs. Given the overall complexity of the immune system and both species- and tissue-specific immune peculiarities, the selection and design of appropriate immune-relevant animal models is, however, not following a straightforward path. The topics in this issue of the ILAR Journal provide assessments of immune-relevant animal models used in oncology, hematopoietic-, CAR-T cell- and xenotransplantation, adjuvants and infectious diseases, and immune privileged inflammation that are providing key insights into unmet human clinical needs.
Original languageEnglish
JournalI L A R Journal
Volume59
Issue number3
Pages (from-to)209-210
ISSN1084-2020
DOIs
Publication statusPublished - 2019

Keywords

  • Animal models
  • Immunology
  • Preclinical validity

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