Integrated B1+ Mapping for Hyperpolarized 13C MRI in a Clinical Setup using Multi-Channel Receive Arrays

Rie Beck Hansen, Peter J. Shin, Jeremy W. Gordon, Mark van Criekinge, Lucas Carvajal, Lars G. Hanson, Jan Henrik Ardenkjær-Larsen, Daniel B. Vigneron

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    Abstract

    For hyperpolarized 13C MRI acquisitions aimed at metabolic rate constant estimation, the Bloch-Siegert shift enables encoding of the transmit field (B1+-field) amplitude within a single hyperpolarized substrate injection. This ability is needed since most clinical hyperpolarized MRI studies use inhomogeneous transmit coils, and because kinetic modeling based on incorrect flip angles can lead to incorrect rate constant estimations. This study demonstrates the feasibility of integrated B1+ mapping for large volume thermal and hyperpolarized phantoms in a clinical setup using a clamshell transmit coil and a 16-channel receive array, and a 3D stack-of-spirals sequence. Phase-sensitive coil-combination was achieved using ESPIRiT.
    Original languageEnglish
    Publication date2018
    Number of pages3
    Publication statusPublished - 2018
    EventJoint Annual Meeting ISMRM-ESMRMB 2018 - Paris Expo Porte de Versailles, Paris, France
    Duration: 16 Jun 201821 Jun 2018
    https://www.ismrm.org/18m/

    Conference

    ConferenceJoint Annual Meeting ISMRM-ESMRMB 2018
    LocationParis Expo Porte de Versailles
    Country/TerritoryFrance
    CityParis
    Period16/06/201821/06/2018
    Internet address

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