Integrated B1+ Mapping for Hyperpolarized 13C MRI in a Clinical Setup using Multi-Channel Receive Arrays

Rie Beck Hansen; Peter J. Shin; Jeremy W. Gordon; Mark van Criekinge; Lucas Carvajal; Lars G.  Hanson; Jan Henrik Ardenkjær-Larsen; Daniel B. Vigneron

Integrated B1+ Mapping for Hyperpolarized 13C MRI in a Clinical Setup using Multi-Channel Receive Arrays

Rie Beck Hansen, Peter J. Shin, Jeremy W. Gordon, Mark van Criekinge, Lucas Carvajal, Lars G. Hanson, Jan Henrik Ardenkjær-Larsen, Daniel B. Vigneron

University of California at San Francisco

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Abstract

For hyperpolarized ¹³C MRI acquisitions aimed at metabolic rate constant estimation, the Bloch-Siegert shift enables encoding of the transmit field (B₁⁺-field) amplitude within a single hyperpolarized substrate injection. This ability is needed since most clinical hyperpolarized MRI studies use inhomogeneous transmit coils, and because kinetic modeling based on incorrect flip angles can lead to incorrect rate constant estimations. This study demonstrates the feasibility of integrated B₁⁺ mapping for large volume thermal and hyperpolarized phantoms in a clinical setup using a clamshell transmit coil and a 16-channel receive array, and a 3D stack-of-spirals sequence. Phase-sensitive coil-combination was achieved using ESPIRiT.

Original language	English
Publication date	2018
Number of pages	3
Publication status	Published - 2018
Event	Joint Annual Meeting ISMRM-ESMRMB 2018 - Paris Expo Porte de Versailles, Paris, France Duration: 16 Jun 2018 → 21 Jun 2018 https://www.ismrm.org/18m/

Conference

Conference	Joint Annual Meeting ISMRM-ESMRMB 2018
Location	Paris Expo Porte de Versailles
Country/Territory	France
City	Paris
Period	16/06/2018 → 21/06/2018
Internet address	https://www.ismrm.org/18m/

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@conference{d66ed94ba87c49ec8673ea3476fe726f,

title = "Integrated B1+ Mapping for Hyperpolarized 13C MRI in a Clinical Setup using Multi-Channel Receive Arrays",

abstract = "For hyperpolarized 13C MRI acquisitions aimed at metabolic rate constant estimation, the Bloch-Siegert shift enables encoding of the transmit field (B1+-field) amplitude within a single hyperpolarized substrate injection. This ability is needed since most clinical hyperpolarized MRI studies use inhomogeneous transmit coils, and because kinetic modeling based on incorrect flip angles can lead to incorrect rate constant estimations. This study demonstrates the feasibility of integrated B1+ mapping for large volume thermal and hyperpolarized phantoms in a clinical setup using a clamshell transmit coil and a 16-channel receive array, and a 3D stack-of-spirals sequence. Phase-sensitive coil-combination was achieved using ESPIRiT.",

author = "Hansen, {Rie Beck} and Shin, {Peter J.} and Gordon, {Jeremy W.} and {van Criekinge}, Mark and Lucas Carvajal and Hanson, {Lars G.} and Ardenkj{\ae}r-Larsen, {Jan Henrik} and Vigneron, {Daniel B.}",

year = "2018",

language = "English",

note = "Joint Annual Meeting ISMRM-ESMRMB 2018 ; Conference date: 16-06-2018 Through 21-06-2018",

url = "https://www.ismrm.org/18m/",

}

TY - ABST

T1 - Integrated B1+ Mapping for Hyperpolarized 13C MRI in a Clinical Setup using Multi-Channel Receive Arrays

AU - Hansen, Rie Beck

AU - Shin, Peter J.

AU - Gordon, Jeremy W.

AU - van Criekinge, Mark

AU - Carvajal, Lucas

AU - Hanson, Lars G.

AU - Ardenkjær-Larsen, Jan Henrik

AU - Vigneron, Daniel B.

PY - 2018

Y1 - 2018

N2 - For hyperpolarized 13C MRI acquisitions aimed at metabolic rate constant estimation, the Bloch-Siegert shift enables encoding of the transmit field (B1+-field) amplitude within a single hyperpolarized substrate injection. This ability is needed since most clinical hyperpolarized MRI studies use inhomogeneous transmit coils, and because kinetic modeling based on incorrect flip angles can lead to incorrect rate constant estimations. This study demonstrates the feasibility of integrated B1+ mapping for large volume thermal and hyperpolarized phantoms in a clinical setup using a clamshell transmit coil and a 16-channel receive array, and a 3D stack-of-spirals sequence. Phase-sensitive coil-combination was achieved using ESPIRiT.

AB - For hyperpolarized 13C MRI acquisitions aimed at metabolic rate constant estimation, the Bloch-Siegert shift enables encoding of the transmit field (B1+-field) amplitude within a single hyperpolarized substrate injection. This ability is needed since most clinical hyperpolarized MRI studies use inhomogeneous transmit coils, and because kinetic modeling based on incorrect flip angles can lead to incorrect rate constant estimations. This study demonstrates the feasibility of integrated B1+ mapping for large volume thermal and hyperpolarized phantoms in a clinical setup using a clamshell transmit coil and a 16-channel receive array, and a 3D stack-of-spirals sequence. Phase-sensitive coil-combination was achieved using ESPIRiT.

M3 - Conference abstract for conference

T2 - Joint Annual Meeting ISMRM-ESMRMB 2018

Y2 - 16 June 2018 through 21 June 2018

ER -

Integrated B1+ Mapping for Hyperpolarized 13C MRI in a Clinical Setup using Multi-Channel Receive Arrays

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