Abstract
With a growing number of cell-based biotechnological applications, there is a need for particle separation systems capable of multiparameter separations at high purity and throughput, beyond what is presently offered by traditional methods including fluorescence activated cell sorting and column-based magnetic separation. Toward this aim, we report on the integration of microfluidic acoustic and magnetic separation in a monolithic device for multiparameter particle separation. Using our device, we demonstrate high-purity separation of a multicomponent particle mixture at a throughput of up to 10(8) particles/hr. (C) 2009 American Institute of Physics. [doi:10.1063/1.3275577]
Original language | English |
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Journal | Applied Physics Letters |
Volume | 95 |
Issue number | 25 |
Pages (from-to) | 254103 |
ISSN | 0003-6951 |
DOIs | |
Publication status | Published - 2009 |