We present an innovative technique to dispense precise amounts of polymer solutions into large arrays of microscopic wells. An inkjet printer (NP 2.1 GeSim, Germany) is used to fill micro-wells with poly (vinyl pyrrolidone) (PVP K10). The micro-wells are fabricated with cavity diameters of 300 μm down to 50 μm with SU-8 with two steps of negative photolithography. Inkjet printing is shown to be a suitable technique to dispense defined volumes of solution (down to 0.3 nL) in a highly reproducible way. The filling with polymer can be controlled varying the concentration of the solution and the number of dispensed droplets. Solutions of up to 20 wt.% PVP in water are successfully spotted.
- Inkjet printing
- Drug delivery