Injectable and adhesive hydrogels for dealing with wounds

Parisa Ghandforoushan, Nasim Golafshan, Firoz Babu Kadumudi, Miguel Castilho, Alireza Dolatshahi-Pirouz, Gorka Orive*

*Corresponding author for this work

Research output: Contribution to journalReviewpeer-review

Abstract

The development of wound dressing materials that combine healing properties, ability to self-repair the material damages, skin-friendly adhesive nature, and competent mechanical properties have surpassing functional importance in healthcare. Due to their specificity, hydrogels have been recognized as a new gateway in biological materials to treat dysfunctional tissues. The design and creation of injectable hydrogel-based scaffolds have extensively progressed in recent years to improve their therapeutic efficacy and to pave the way for their easy minimally invasive administration. Hence, injectable hydrogel biomaterials have been prepared to eventually translate into minimally invasive therapy and pose a lasting effect on regenerative medicine.
This review highlights the recent development of adhesive and injectable hydrogels that have applications in wound healing and wound dressing. Such hydrogel materials are not only expected to improve therapeutic outcomes but also to facilitate the easy surgical process in both wound healing and dressing.
Wound healing seems to be an appealing approach for treating countless life-threatening disorders. With the average increase of life expectancy in human societies, an increase in demand for injectable skin replacements and drug delivery carriers for chronic wound healing is expected.
Original languageEnglish
JournalExpert Opinion on Biological Therapy
Number of pages15
ISSN1471-2598
DOIs
Publication statusAccepted/In press - 2022

Keywords

  • Adhesive
  • Biomaterials
  • Injectable hydrogel
  • Medical applications
  • Tissue engineering
  • Wound healing

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