Inhibitors of crispr-cas associated activity

Ruben Vazquez-Uribe (Inventor), Eric Van Der Helm (Inventor), Morten Otto Alexander Sommer (Inventor), Maria-Anna Misiakou (Inventor), Sang Woo Lee (Inventor)

Research output: Patent

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The invention relates to Acr proteins capable of regulating CRISPR-Cas associated activity, and their use in regulating CRISPR-Cas associated activity within a biological cell. The invention further provides nucleic acid molecules and self-replications genetic elements adapted for expression of said Acr proteins, or for their co-expression with a cognate CRISPR-Cas system in a biological cell.

Original languageEnglish
IPCC12N 15/ 90 A I
Patent numberWO2019185751
Filing date27/03/2019
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date27/03/2018
Priority numberEP20180164238
Publication statusPublished - 3 Oct 2019


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