The invention relates to Acr proteins capable of regulating CRISPR-Cas associated activity, and their use in regulating CRISPR-Cas associated activity within a biological cell. The invention further provides nucleic acid molecules and self-replications genetic elements adapted for expression of said Acr proteins, or for their co-expression with a cognate CRISPR-Cas system in a biological cell.
|IPC||C12N 15/ 90 A I|
|Country||International Bureau of the World Intellectual Property Organization (WIPO)|
|Publication status||Published - 3 Oct 2019|