Abstract
The invention relates to Acr proteins capable of regulating CRISPR-Cas associated activity, and their use in regulating CRISPR-Cas associated activity within a biological cell. The invention further provides nucleic acid molecules and self-replications genetic elements adapted for expression of said Acr proteins, or for their co-expression with a cognate CRISPR-Cas system in a biological cell.
| Original language | English |
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| IPC | C12N 15/ 90 A I |
| Patent number | WO2019185751 |
| Filing date | 27/03/2019 |
| Country | International Bureau of the World Intellectual Property Organization (WIPO) |
| Priority date | 27/03/2018 |
| Priority number | EP20180164238 |
| Publication status | Published - 3 Oct 2019 |