TY - JOUR
T1 - Induction of porcine post-weaning multisystemic wasting syndrome (PMWS) in pigs from PMWS unaffected herds following mingling with pigs from PMWS-affected herds
AU - Kristensen, Charlotte Sonne
AU - Bækbo, Poul
AU - Bille-Hansen, Vivi
AU - Bøtner, Anette
AU - Vigre, Håkan
AU - Enøe, Claes
AU - Larsen, Lars Erik
PY - 2009
Y1 - 2009
N2 - In this paper we present the results from two experimental studies (I and II) investigating
whether post-weaning multisystemic wasting syndrome (PMWS) can be induced in pigs
from PMWS unaffected herds by mingling with pigs from PMWS-affected herds and to
observe whether transportation and/or mingling of healthy pigs from unaffected herds
could induce PMWS.
The studies comprised pigs from 12 different herds. Eight herds had PMWS while four
were unaffected. All 12 herds were found to be infected with PCV2. Pigs from PMWSaffected
herds were mingled with pigs from unaffected herds in four separate
compartments in both study I and study II. In addition, in study II, four groups of pigs
from unaffected herds were included. Two groups with pigs transported and mingled from
unaffected herds and two groups with pigs which were only transported. The PMWS
diagnoses on the individual pigs were based on lymphoid depletion, histiocytic
proliferation and the presence of giant cells or inclusion bodies together with the
demonstration of PCV2 in lymphoid tissue.
Healthy pigs, in both studies, developed PMWS 4–5 weeks after mingling with pigs
clinically affected with PMWS. None of the pigs from unaffected herds which had no
contact with pigs from PMWS-affected herds developed clinical signs of PMWS.
Transportation and mingling of pigs from PMWS unaffected herds in combination or
alone was insufficient to provoke PMWS.
AB - In this paper we present the results from two experimental studies (I and II) investigating
whether post-weaning multisystemic wasting syndrome (PMWS) can be induced in pigs
from PMWS unaffected herds by mingling with pigs from PMWS-affected herds and to
observe whether transportation and/or mingling of healthy pigs from unaffected herds
could induce PMWS.
The studies comprised pigs from 12 different herds. Eight herds had PMWS while four
were unaffected. All 12 herds were found to be infected with PCV2. Pigs from PMWSaffected
herds were mingled with pigs from unaffected herds in four separate
compartments in both study I and study II. In addition, in study II, four groups of pigs
from unaffected herds were included. Two groups with pigs transported and mingled from
unaffected herds and two groups with pigs which were only transported. The PMWS
diagnoses on the individual pigs were based on lymphoid depletion, histiocytic
proliferation and the presence of giant cells or inclusion bodies together with the
demonstration of PCV2 in lymphoid tissue.
Healthy pigs, in both studies, developed PMWS 4–5 weeks after mingling with pigs
clinically affected with PMWS. None of the pigs from unaffected herds which had no
contact with pigs from PMWS-affected herds developed clinical signs of PMWS.
Transportation and mingling of pigs from PMWS unaffected herds in combination or
alone was insufficient to provoke PMWS.
U2 - 10.1016/j.vetmic.2009.04.004
DO - 10.1016/j.vetmic.2009.04.004
M3 - Journal article
SN - 0378-1135
VL - 138
SP - 244
EP - 250
JO - Veterinary Microbiology
JF - Veterinary Microbiology
ER -