TY - JOUR
T1 - Indole alkaloids and terpenoids from Tabernaemontana markgrafiana
AU - Nielsen, H.B.
AU - Hazell, A.
AU - Hazell, R.
AU - Ghia, F.
AU - Torssell, K.B.G.
PY - 1994
Y1 - 1994
N2 - The bark of Tabernaemontana markgrafiana yielded five acetylated pentacyclic triterpenes and 24 monoterpene indole alkaloids. The major triterpene was baurenyl acetate, which constituted ca 6% of the crude petrol extract. An X-ray study of iso-ursenyl acetate was carried out for the first time. The indole alkaloids were primarily of the iboga-type and constituted ca 3% of the dried bark and 20% of the total extracts. The major alkaloids were coronaridine, (19S)-heyneanine, voacangine and ibogamine. Among the minor components, four new alkaloids were identified: 5,6-dehydro-coronaridine, 3R-methoxy-coronaridine, 3R-methoxyvoacangine and the 10,11-demethoxy chippiine.
AB - The bark of Tabernaemontana markgrafiana yielded five acetylated pentacyclic triterpenes and 24 monoterpene indole alkaloids. The major triterpene was baurenyl acetate, which constituted ca 6% of the crude petrol extract. An X-ray study of iso-ursenyl acetate was carried out for the first time. The indole alkaloids were primarily of the iboga-type and constituted ca 3% of the dried bark and 20% of the total extracts. The major alkaloids were coronaridine, (19S)-heyneanine, voacangine and ibogamine. Among the minor components, four new alkaloids were identified: 5,6-dehydro-coronaridine, 3R-methoxy-coronaridine, 3R-methoxyvoacangine and the 10,11-demethoxy chippiine.
U2 - 10.1016/S0031-9422(00)89601-6
DO - 10.1016/S0031-9422(00)89601-6
M3 - Journal article
SN - 0031-9422
VL - 37
SP - 1729
EP - 1735
JO - Phytochemistry
JF - Phytochemistry
IS - 6
ER -