In Vivo Phenotyping of Tumor Metabolism in a Canine Cancer Patient with Simultaneous (18)F-FDG-PET and Hyperpolarized (13)C-Pyruvate Magnetic Resonance Spectroscopic Imaging (hyperPET): Mismatch Demonstrates that FDG may not Always Reflect the Warburg Effect

Henrik Gutte, Adam E Hansen, Majbrit M E Larsen, Sofie Rahbek, Helle H Johannesen, Jan Henrik Ardenkjær-Larsen, Annemarie T Kristensen, Liselotte Højgaard, Andreas Kjær

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Abstract

In this communication the mismatch between simultaneous (18)F-FDG-PET and a (13)C-lactate imaging (hyperPET) in a biopsy verified squamous cell carcinoma in the right tonsil of a canine cancer patient is shown. The results demonstrate that (18)F-FDG-PET may not always reflect the Warburg effect in all tumors.
Original languageEnglish
JournalDiagnostics
Volume5
Issue number3
Pages (from-to)287–289
ISSN2075-4418
DOIs
Publication statusPublished - 2015

Keywords

  • 13C-pyruvate
  • 18F-FDG-PET
  • MR
  • PET/MR
  • Cancer
  • Dynamic nuclear polarization
  • HyperPET
  • Hyperpolarized
  • Molecular imaging

Cite this

@article{2d825eea631e40fdbee9bfde7287557e,
title = "In Vivo Phenotyping of Tumor Metabolism in a Canine Cancer Patient with Simultaneous (18)F-FDG-PET and Hyperpolarized (13)C-Pyruvate Magnetic Resonance Spectroscopic Imaging (hyperPET): Mismatch Demonstrates that FDG may not Always Reflect the Warburg Effect",
abstract = "In this communication the mismatch between simultaneous (18)F-FDG-PET and a (13)C-lactate imaging (hyperPET) in a biopsy verified squamous cell carcinoma in the right tonsil of a canine cancer patient is shown. The results demonstrate that (18)F-FDG-PET may not always reflect the Warburg effect in all tumors.",
keywords = "13C-pyruvate, 18F-FDG-PET, MR, PET/MR, Cancer, Dynamic nuclear polarization, HyperPET, Hyperpolarized, Molecular imaging",
author = "Henrik Gutte and Hansen, {Adam E} and Larsen, {Majbrit M E} and Sofie Rahbek and Johannesen, {Helle H} and Ardenkj{\ae}r-Larsen, {Jan Henrik} and Kristensen, {Annemarie T} and Liselotte H{\o}jgaard and Andreas Kj{\ae}r",
year = "2015",
doi = "10.3390/diagnostics5030287",
language = "English",
volume = "5",
pages = "287–289",
journal = "Diagnostics",
issn = "2075-4418",
publisher = "MDPI AG",
number = "3",

}

In Vivo Phenotyping of Tumor Metabolism in a Canine Cancer Patient with Simultaneous (18)F-FDG-PET and Hyperpolarized (13)C-Pyruvate Magnetic Resonance Spectroscopic Imaging (hyperPET): Mismatch Demonstrates that FDG may not Always Reflect the Warburg Effect. / Gutte, Henrik; Hansen, Adam E; Larsen, Majbrit M E; Rahbek, Sofie; Johannesen, Helle H; Ardenkjær-Larsen, Jan Henrik; Kristensen, Annemarie T; Højgaard, Liselotte; Kjær, Andreas .

In: Diagnostics, Vol. 5, No. 3, 2015, p. 287–289.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - In Vivo Phenotyping of Tumor Metabolism in a Canine Cancer Patient with Simultaneous (18)F-FDG-PET and Hyperpolarized (13)C-Pyruvate Magnetic Resonance Spectroscopic Imaging (hyperPET): Mismatch Demonstrates that FDG may not Always Reflect the Warburg Effect

AU - Gutte, Henrik

AU - Hansen, Adam E

AU - Larsen, Majbrit M E

AU - Rahbek, Sofie

AU - Johannesen, Helle H

AU - Ardenkjær-Larsen, Jan Henrik

AU - Kristensen, Annemarie T

AU - Højgaard, Liselotte

AU - Kjær, Andreas

PY - 2015

Y1 - 2015

N2 - In this communication the mismatch between simultaneous (18)F-FDG-PET and a (13)C-lactate imaging (hyperPET) in a biopsy verified squamous cell carcinoma in the right tonsil of a canine cancer patient is shown. The results demonstrate that (18)F-FDG-PET may not always reflect the Warburg effect in all tumors.

AB - In this communication the mismatch between simultaneous (18)F-FDG-PET and a (13)C-lactate imaging (hyperPET) in a biopsy verified squamous cell carcinoma in the right tonsil of a canine cancer patient is shown. The results demonstrate that (18)F-FDG-PET may not always reflect the Warburg effect in all tumors.

KW - 13C-pyruvate

KW - 18F-FDG-PET

KW - MR

KW - PET/MR

KW - Cancer

KW - Dynamic nuclear polarization

KW - HyperPET

KW - Hyperpolarized

KW - Molecular imaging

U2 - 10.3390/diagnostics5030287

DO - 10.3390/diagnostics5030287

M3 - Journal article

C2 - 26854154

VL - 5

SP - 287

EP - 289

JO - Diagnostics

JF - Diagnostics

SN - 2075-4418

IS - 3

ER -