In vitro screening of Indian medicinal plants for antiplasmodial activity

Henrik Toft Simonsen; Jesper Brændegaard Nordskjold; Ulla Wagner Smitt; Ulf Nyman; Pushpangadan Palpu; Prabhakar Joshi; George Varughese

doi:10.1016/S0378-8741(00)00369-X

In vitro screening of Indian medicinal plants for antiplasmodial activity

Henrik Toft Simonsen, Jesper Brændegaard Nordskjold, Ulla Wagner Smitt, Ulf Nyman, Pushpangadan Palpu, Prabhakar Joshi, George Varughese

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Plants traditionally used in India to treat fever or malaria were examined in vitro for antiplasmodial properties against Plasmodium falciparum. Of 80 analysed ethanol extracts, from 47 species, significant effects were found for 31 of the extracts. These represent 23 different species from 20 families. Of the active species 20 were tested against P. falciparum for the first time. The following five species seems to be of special interest for further antimalarial studies, Casearia elliptica, Holarrhena pubescens, Pongamia pinnata, Soymida febrifuga, and Plumbago zeylanica.

Original language	English
Journal	Journal of Ethnopharmacology
Volume	74
Issue number	2
Pages (from-to)	195-204
Number of pages	10
ISSN	0378-8741
DOIs	https://doi.org/10.1016/S0378-8741(00)00369-X
Publication status	Published - 2001
Externally published	Yes

Keywords

Indian plants
Ethnopharmacology
Antiplasmodial
Malaria
Plasmodium falciparum
In vitro screening

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0378-8741(00)00369-X

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title = "In vitro screening of Indian medicinal plants for antiplasmodial activity",

abstract = "Plants traditionally used in India to treat fever or malaria were examined in vitro for antiplasmodial properties against Plasmodium falciparum. Of 80 analysed ethanol extracts, from 47 species, significant effects were found for 31 of the extracts. These represent 23 different species from 20 families. Of the active species 20 were tested against P. falciparum for the first time. The following five species seems to be of special interest for further antimalarial studies, Casearia elliptica, Holarrhena pubescens, Pongamia pinnata, Soymida febrifuga, and Plumbago zeylanica.",

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author = "Simonsen, {Henrik Toft} and Nordskjold, {Jesper Br{\ae}ndegaard} and Smitt, {Ulla Wagner} and Ulf Nyman and Pushpangadan Palpu and Prabhakar Joshi and George Varughese",

year = "2001",

doi = "10.1016/S0378-8741(00)00369-X",

language = "English",

volume = "74",

pages = "195--204",

journal = "Journal of Ethnopharmacology",

issn = "0378-8741",

publisher = "Elsevier",

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TY - JOUR

T1 - In vitro screening of Indian medicinal plants for antiplasmodial activity

AU - Simonsen, Henrik Toft

AU - Nordskjold, Jesper Brændegaard

AU - Smitt, Ulla Wagner

AU - Nyman, Ulf

AU - Palpu, Pushpangadan

AU - Joshi, Prabhakar

AU - Varughese, George

PY - 2001

Y1 - 2001

N2 - Plants traditionally used in India to treat fever or malaria were examined in vitro for antiplasmodial properties against Plasmodium falciparum. Of 80 analysed ethanol extracts, from 47 species, significant effects were found for 31 of the extracts. These represent 23 different species from 20 families. Of the active species 20 were tested against P. falciparum for the first time. The following five species seems to be of special interest for further antimalarial studies, Casearia elliptica, Holarrhena pubescens, Pongamia pinnata, Soymida febrifuga, and Plumbago zeylanica.

AB - Plants traditionally used in India to treat fever or malaria were examined in vitro for antiplasmodial properties against Plasmodium falciparum. Of 80 analysed ethanol extracts, from 47 species, significant effects were found for 31 of the extracts. These represent 23 different species from 20 families. Of the active species 20 were tested against P. falciparum for the first time. The following five species seems to be of special interest for further antimalarial studies, Casearia elliptica, Holarrhena pubescens, Pongamia pinnata, Soymida febrifuga, and Plumbago zeylanica.

KW - Indian plants

KW - Ethnopharmacology

KW - Antiplasmodial

KW - Malaria

KW - Plasmodium falciparum

KW - In vitro screening

U2 - 10.1016/S0378-8741(00)00369-X

DO - 10.1016/S0378-8741(00)00369-X

M3 - Journal article

SN - 0378-8741

VL - 74

SP - 195

EP - 204

JO - Journal of Ethnopharmacology

JF - Journal of Ethnopharmacology

IS - 2

ER -

In vitro screening of Indian medicinal plants for antiplasmodial activity

Abstract

Keywords

UN SDGs

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