In vitro production of bovine embryos: cumulus/granulosa cell gene expression patterns point to early atresia as beneficial for oocyte competence

Gianluca Mazzoni, Eduardo Razza, Hanne S. Pedersen, Jan Secher, Haja Kadarmideen, Henrik Callesen, Lotte Stroebech, Kristine Freude, Poul Hyttel

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    Abstract

    In vitro production (IW) of bovine embryos has become widespread technology implemented in cattle breeding and production. Here, we review novel data on cumulus/granulosa cell gene expression, as determined by RNAseq on cellular material from pooled follicular fluids at the single animal level, and relate these finding to previous data on oocyte developmental competence and ultrastructure. The cumulus/granulosa cell gene expression patterns indicate that early follicular atresia is associated with increased blastocyst yield and this hypothesis is supported by previous data on oocyte competence and ultrastructure.
    Original languageEnglish
    Title of host publicationProceedings of the 31th Annual Meeting of the Brazilian Embryo Technology Society (SBTE)
    Number of pages8
    Volume14
    Publication date2017
    Pages482-489
    DOIs
    Publication statusPublished - 2017
    Event31st Annual Meeting of the Brazilian Embryo Technology Society - , Brazil
    Duration: 17 Aug 201719 Aug 2017

    Conference

    Conference31st Annual Meeting of the Brazilian Embryo Technology Society
    Country/TerritoryBrazil
    Period17/08/201719/08/2017
    SeriesAnimal Reproduction Science
    ISSN0378-4320

    Keywords

    • IVP
    • Biomarkers
    • Transcriptomics
    • Granulosa cells
    • Atresia
    • Cattle
    • Oocyte competence

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