In-house validation of a method for determination of silver nanoparticles in chicken meat based on asymmetric flow field-flow fractionation and inductively coupled plasma mass spectrometric detection

Katrin Löschner; Jana Navratilova; Ringo Grombe; Thomas P.J. Linsinger; Carsten Købler; Kristian Mølhave; Erik Huusfeldt Larsen

doi:10.1016/j.foodchem.2015.02.033

In-house validation of a method for determination of silver nanoparticles in chicken meat based on asymmetric flow field-flow fractionation and inductively coupled plasma mass spectrometric detection

Katrin Löschner, Jana Navratilova, Ringo Grombe, Thomas P.J. Linsinger, Carsten Købler, Kristian Mølhave, Erik Huusfeldt Larsen

National Food Institute

European Commission

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Nanomaterials are increasingly used in food production and packaging, and validated methods for detection of nanoparticles (NPs) in foodstuffs need to be developed both for regulatory purposes and product development. Asymmetric flow field-flow fractionation with inductively coupled plasma mass spectrometric detection (AF4-ICP-MS) was applied for quantitative analysis of silver nanoparticles (AgNPs) in a chicken meat matrix following enzymatic sample preparation. For the first time an analytical validation of nanoparticle detection in a food matrix by AF4-ICP-MS has been carried out and the results showed repeatable and intermediately reproducible determination of AgNP mass fraction and size. The findings demonstrated the potential of AF4-ICP-MS for quantitative analysis of NPs in complex food matrices for use in food monitoring and control. The accurate determination of AgNP size distribution remained challenging due to the lack of certified size standards.

Original language	English
Journal	Food Chemistry
Volume	181
Pages (from-to)	78-84
Number of pages	7
ISSN	0308-8146
DOIs	https://doi.org/10.1016/j.foodchem.2015.02.033
Publication status	Published - 2015

Keywords

Enzymatic digestion
Field-flow fractionation
Silver nanoparticles
Single particle ICP-MS
Validation
Animals
Flow fields
Fractionation
Inductively coupled plasma
Inductively coupled plasma mass spectrometry
Liquid chromatography
Mass spectrometers
Meats
Nanoparticles
Product development
Spectrometry
Enzymatic digestions
Field flow fractionation
Single particle
Silver

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.foodchem.2015.02.033

OpenUrl availability

Full text

Cite this

Löschner, K., Navratilova, J., Grombe, R., Linsinger, T. P. J., Købler, C., Mølhave, K., & Larsen, E. H. (2015). In-house validation of a method for determination of silver nanoparticles in chicken meat based on asymmetric flow field-flow fractionation and inductively coupled plasma mass spectrometric detection. Food Chemistry, 181, 78-84. https://doi.org/10.1016/j.foodchem.2015.02.033

@article{040ee53015414ab4b88563c5e32f5eeb,

title = "In-house validation of a method for determination of silver nanoparticles in chicken meat based on asymmetric flow field-flow fractionation and inductively coupled plasma mass spectrometric detection",

abstract = "Nanomaterials are increasingly used in food production and packaging, and validated methods for detection of nanoparticles (NPs) in foodstuffs need to be developed both for regulatory purposes and product development. Asymmetric flow field-flow fractionation with inductively coupled plasma mass spectrometric detection (AF4-ICP-MS) was applied for quantitative analysis of silver nanoparticles (AgNPs) in a chicken meat matrix following enzymatic sample preparation. For the first time an analytical validation of nanoparticle detection in a food matrix by AF4-ICP-MS has been carried out and the results showed repeatable and intermediately reproducible determination of AgNP mass fraction and size. The findings demonstrated the potential of AF4-ICP-MS for quantitative analysis of NPs in complex food matrices for use in food monitoring and control. The accurate determination of AgNP size distribution remained challenging due to the lack of certified size standards.",

keywords = "Enzymatic digestion, Field-flow fractionation, Silver nanoparticles, Single particle ICP-MS, Validation, Animals, Flow fields, Fractionation, Inductively coupled plasma, Inductively coupled plasma mass spectrometry, Liquid chromatography, Mass spectrometers, Meats, Nanoparticles, Product development, Spectrometry, Enzymatic digestions, Field flow fractionation, Single particle, Silver",

author = "Katrin L{\"o}schner and Jana Navratilova and Ringo Grombe and Linsinger, {Thomas P.J.} and Carsten K{\o}bler and Kristian M{\o}lhave and Larsen, {Erik Huusfeldt}",

year = "2015",

doi = "10.1016/j.foodchem.2015.02.033",

language = "English",

volume = "181",

pages = "78--84",

journal = "Food Chemistry",

issn = "0308-8146",

publisher = "Elsevier",

}

Löschner, K, Navratilova, J, Grombe, R, Linsinger, TPJ, Købler, C, Mølhave, K & Larsen, EH 2015, 'In-house validation of a method for determination of silver nanoparticles in chicken meat based on asymmetric flow field-flow fractionation and inductively coupled plasma mass spectrometric detection', Food Chemistry, vol. 181, pp. 78-84. https://doi.org/10.1016/j.foodchem.2015.02.033

In-house validation of a method for determination of silver nanoparticles in chicken meat based on asymmetric flow field-flow fractionation and inductively coupled plasma mass spectrometric detection. / Löschner, Katrin; Navratilova, Jana; Grombe, Ringo et al.
In: Food Chemistry, Vol. 181, 2015, p. 78-84.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - In-house validation of a method for determination of silver nanoparticles in chicken meat based on asymmetric flow field-flow fractionation and inductively coupled plasma mass spectrometric detection

AU - Löschner, Katrin

AU - Navratilova, Jana

AU - Grombe, Ringo

AU - Linsinger, Thomas P.J.

AU - Købler, Carsten

AU - Mølhave, Kristian

AU - Larsen, Erik Huusfeldt

PY - 2015

Y1 - 2015

N2 - Nanomaterials are increasingly used in food production and packaging, and validated methods for detection of nanoparticles (NPs) in foodstuffs need to be developed both for regulatory purposes and product development. Asymmetric flow field-flow fractionation with inductively coupled plasma mass spectrometric detection (AF4-ICP-MS) was applied for quantitative analysis of silver nanoparticles (AgNPs) in a chicken meat matrix following enzymatic sample preparation. For the first time an analytical validation of nanoparticle detection in a food matrix by AF4-ICP-MS has been carried out and the results showed repeatable and intermediately reproducible determination of AgNP mass fraction and size. The findings demonstrated the potential of AF4-ICP-MS for quantitative analysis of NPs in complex food matrices for use in food monitoring and control. The accurate determination of AgNP size distribution remained challenging due to the lack of certified size standards.

AB - Nanomaterials are increasingly used in food production and packaging, and validated methods for detection of nanoparticles (NPs) in foodstuffs need to be developed both for regulatory purposes and product development. Asymmetric flow field-flow fractionation with inductively coupled plasma mass spectrometric detection (AF4-ICP-MS) was applied for quantitative analysis of silver nanoparticles (AgNPs) in a chicken meat matrix following enzymatic sample preparation. For the first time an analytical validation of nanoparticle detection in a food matrix by AF4-ICP-MS has been carried out and the results showed repeatable and intermediately reproducible determination of AgNP mass fraction and size. The findings demonstrated the potential of AF4-ICP-MS for quantitative analysis of NPs in complex food matrices for use in food monitoring and control. The accurate determination of AgNP size distribution remained challenging due to the lack of certified size standards.

KW - Enzymatic digestion

KW - Field-flow fractionation

KW - Silver nanoparticles

KW - Single particle ICP-MS

KW - Validation

KW - Animals

KW - Flow fields

KW - Fractionation

KW - Inductively coupled plasma

KW - Inductively coupled plasma mass spectrometry

KW - Liquid chromatography

KW - Mass spectrometers

KW - Meats

KW - Nanoparticles

KW - Product development

KW - Spectrometry

KW - Enzymatic digestions

KW - Field flow fractionation

KW - Single particle

KW - Silver

U2 - 10.1016/j.foodchem.2015.02.033

DO - 10.1016/j.foodchem.2015.02.033

M3 - Journal article

C2 - 25794724

SN - 0308-8146

VL - 181

SP - 78

EP - 84

JO - Food Chemistry

JF - Food Chemistry

ER -

In-house validation of a method for determination of silver nanoparticles in chicken meat based on asymmetric flow field-flow fractionation and inductively coupled plasma mass spectrometric detection

Abstract

Keywords

UN SDGs

Access to Document

OpenUrl availability

Fingerprint

Cite this