Improving Reproducibility in Synthetic Biology

Mathew M. Jessop-Fabre, Nikolaus Sonnenschein*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

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Abstract

Synthetic biology holds great promise to deliver transformative technologies to the world in the coming years. However, several challenges still remain to be addressed before it can deliver on its promises. One of the most important issues to address is the lack of reproducibility within research of the life sciences. This problem is beginning to be recognised by the community and solutions are being developed to tackle the problem. The recent emergence of automated facilities that are open for use by researchers (such as biofoundries and cloud labs) may be one of the ways that synthetic biologists can improve the quality and reproducibility of their work. In this perspective article, we outline these and some of the other technologies that are currently being developed which we believe may help to transform how synthetic biologists approach their research activities.
Original languageEnglish
Article number18
JournalFrontiers in Bioengineering and Biotechnology
Volume7
Number of pages6
ISSN2296-4185
DOIs
Publication statusPublished - 2019

Keywords

  • Synthetic biology
  • utomation
  • Reproducibility
  • Cloud lab
  • Biofoundry

Cite this

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Improving Reproducibility in Synthetic Biology. / Jessop-Fabre, Mathew M.; Sonnenschein, Nikolaus.

In: Frontiers in Bioengineering and Biotechnology, Vol. 7, 18, 2019.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

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AU - Sonnenschein, Nikolaus

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AB - Synthetic biology holds great promise to deliver transformative technologies to the world in the coming years. However, several challenges still remain to be addressed before it can deliver on its promises. One of the most important issues to address is the lack of reproducibility within research of the life sciences. This problem is beginning to be recognised by the community and solutions are being developed to tackle the problem. The recent emergence of automated facilities that are open for use by researchers (such as biofoundries and cloud labs) may be one of the ways that synthetic biologists can improve the quality and reproducibility of their work. In this perspective article, we outline these and some of the other technologies that are currently being developed which we believe may help to transform how synthetic biologists approach their research activities.

KW - Synthetic biology

KW - utomation

KW - Reproducibility

KW - Cloud lab

KW - Biofoundry

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