Improvement of predictive tools for vapor-liquid equilibrium based on group contribution methods applied to lipid technology

Daniela S. Damaceno, Olivia A. Perederic, Roberta Ceriani, Georgios M. Kontogeorgis*, Rafiqul Gani

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

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Predictive methodologies based on group contribution methods, such as UNIFAC, play a very important role in the design, analysis and optimization of separation processes found in oils, fats and biodiesel industries. However, the UNIFAC model has well-known limitations for complex molecular structures that the first-order functional groups are unable to handle. In the particular case of fatty systems these models are not able to adequately predict the non-ideality in the liquid phase. Consequently, a new set of functional groups is proposed to represent the lipid compounds, requiring thereby, new group interaction parameters. In this work, the performance of several UNIFAC variants, the Original-UNIFAC, the Linear-UNIFAC, Modified-UNIFAC and the Dortmund-UNIFAC is compared. The same set of experimental data and the parameter estimation method developed by Perederic et al. (2017) have been used. The database of measured data comes from a special lipids database developed in-house (SPEED Lipids database at KT-consortium, DTU, Denmark). All UNIFAC models using the new lipid-based parameters show, on average, improvements compared to the same models with their published parameters. There are rather small differences between the models and no single model is the best in all cases.
Original languageEnglish
JournalFluid Phase Equilibria
Pages (from-to)249-258
Publication statusPublished - 2018


  • Lipids
  • Activity coefficient models
  • Original
  • Linear
  • Modified
  • Dortmund


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