Targeted cancer nanotherapeutics offers numerous opportunities for the selective uptake of toxic chemotherapies within tumors and cancer cells. The unique properties of nanoparticles, such as their small size, large surface-to-volume ratios, and the ability to achieve multivalency of targeting ligands on their surface, provide superior advantages for nanoparticle-based drug delivery to a variety of cancers. This review highlights various key concepts in the design of targeted nanotherapeutics for cancer therapy, and discusses physicochemical parameters affecting nanoparticle targeting, along with recent developments for cancer-targeted nanomedicines.
|Title of host publication||Cancer nanotechnology: Methods and Protocols|
|Number of pages||2|
|Publication status||Published - 2017|
|Series||Methods in Molecular Biology|
- Drug delivery
Foster, C., Watson, A., Kaplinsky, J. J., & Kamaly, N. (2017). Improved Targeting of Cancers with Nanotherapeutics. In R. Zeineldin (Ed.), Cancer nanotechnology: Methods and Protocols (Vol. 1530, pp. 13-37). Springer. Methods in Molecular Biology https://doi.org/10.1007/978-1-4939-6646-2_2