Identification of a novel, invasive, not-yet-cultivated Treponema sp in the large intestine of pigs by PCR amplification of the 16S rRNA gene

Lars Mølbak, Kirstine Klitgaard Schou, Tim Kåre Jensen, Marja Fossi, Mette Boye

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    Laser capture microdissection in combination with fluorescent in situ hybridization was used to identify an unknown species of spirochetes from the pig colonic mucosa. The 16S rRNA gene was PCR amplified, and the closest related type strain was Treponema bryantii(T) (90.1%). The spirochete, here named "Candidatus Treponema suis," was associated with colitis, including invasion of the surface epithelium as well as superficial parts of the mucosa.
    Original languageEnglish
    JournalJournal of Clinical Microbiology
    Volume44
    Issue number12
    Pages (from-to)4537-4540
    ISSN0095-1137
    DOIs
    Publication statusPublished - 2006

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