TY - GEN
T1 - Hyperpolarized xenon by d-DNP using the clinical GE SpinLab polarizer system
AU - Mariager, Christian Østergaard
AU - Ringgaard, Steffen
AU - Ardenkjær-Larsen, Jan Henrik
AU - Laustsen, Christoffer
PY - 2017
Y1 - 2017
N2 - Hyperpolarized (HP) 129Xe have been demonstrated as a useful probe for magnetic resonance (MR) lung imaging and show promise for in vivo perfusion imaging and brown adipose tissue characterization. Reports of large polarization enhancements for 129Xe using dynamic nuclearpolarization (DNP) have raised expectations that DNP can be an alternative to the standard spin exchange optical pumping (SEOP) method. We show that it is possible to produce HP 129Xe gas using the clinical GE SpinLab polarizer, thus extending the practical use of the system beyond the primary purpose of hyperpolarizing liquid biomolecules.
AB - Hyperpolarized (HP) 129Xe have been demonstrated as a useful probe for magnetic resonance (MR) lung imaging and show promise for in vivo perfusion imaging and brown adipose tissue characterization. Reports of large polarization enhancements for 129Xe using dynamic nuclearpolarization (DNP) have raised expectations that DNP can be an alternative to the standard spin exchange optical pumping (SEOP) method. We show that it is possible to produce HP 129Xe gas using the clinical GE SpinLab polarizer, thus extending the practical use of the system beyond the primary purpose of hyperpolarizing liquid biomolecules.
M3 - Article in proceedings
T3 - Ismrm 2017 Proceedings
BT - Proceedings of ISMRM 25th Annual Meeting & Exhibition
T2 - ISMRM 25th Annual Meeting & Exhibition
Y2 - 22 April 2017 through 27 April 2017
ER -