Hyperpolarized xenon by d-DNP using the clinical GE SpinLab polarizer system

Christian Østergaard Mariager, Steffen Ringgaard, Jan Henrik Ardenkjær-Larsen, Christoffer Laustsen

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Abstract

Hyperpolarized (HP) 129Xe have been demonstrated as a useful probe for magnetic resonance (MR) lung imaging and show promise for in vivo perfusion imaging and brown adipose tissue characterization. Reports of large polarization enhancements for 129Xe using dynamic nuclearpolarization (DNP) have raised expectations that DNP can be an alternative to the standard spin exchange optical pumping (SEOP) method. We show that it is possible to produce HP 129Xe gas using the clinical GE SpinLab polarizer, thus extending the practical use of the system beyond the primary purpose of hyperpolarizing liquid biomolecules.
Original languageEnglish
Title of host publicationProceedings of ISMRM 25th Annual Meeting & Exhibition
Publication date2017
Publication statusPublished - 2017
Event ISMRM 25th Annual Meeting & Exhibition - Hawai'i Convention Center, Honolulu, United States
Duration: 22 Apr 201727 Apr 2017

Conference

Conference ISMRM 25th Annual Meeting & Exhibition
LocationHawai'i Convention Center
CountryUnited States
CityHonolulu
Period22/04/201727/04/2017
SeriesIsmrm 2017 Proceedings

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