Hyperpolarized esters as metabolic markers in mr

Pernille Rose Jensen; Mathilde Hauge Lerche; Magnus Karlsson; Claudia Cabella; Sonia Colombo Serra; Luigi Miragoli; Luca Venturi; Fabio Tedoldi

Hyperpolarized esters as metabolic markers in mr

Pernille Rose Jensen (Inventor), Mathilde Hauge Lerche (Inventor), Magnus Karlsson (Inventor), Claudia Cabella (Inventor), Sonia Colombo Serra (Inventor), Luigi Miragoli (Inventor), Luca Venturi (Inventor), Fabio Tedoldi (Inventor)

Bracco Imaging

Research output: Patent

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Abstract

The invention relates to a method of Magnetic Resonance (MR) detection, in particular 13C-MR detection, by using a diagnostic medium comprising a hyperpolarized ester, in particular ethyl acetoacetate. The method comprises the detection of the MR signal of a hyperpolarized 13C carboxylic ester and of its respective hyperpolarized metabolite.

Original language	English
IPC	A61K 49/ 10 A I
Patent number	EP2950826
Filing date	09/12/2015
Country/Territory	International Bureau of the World Intellectual Property Organization (WIPO)
Priority date	30/01/2014
Priority number	EP20140704304
Publication status	Published - 9 Dec 2015
Externally published	Yes

Bibliographical note

Also published as: WO2014118258 (A1) US2015374854 (A1) KR20150111353 (A) JP2016504945 (A) CN104981256 (A)

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title = "Hyperpolarized esters as metabolic markers in mr",

abstract = "The invention relates to a method of Magnetic Resonance (MR) detection, in particular 13C-MR detection, by using a diagnostic medium comprising a hyperpolarized ester, in particular ethyl acetoacetate. The method comprises the detection of the MR signal of a hyperpolarized 13C carboxylic ester and of its respective hyperpolarized metabolite.",

author = "Jensen, {Pernille Rose} and Lerche, {Mathilde Hauge} and Magnus Karlsson and Claudia Cabella and {Colombo Serra}, Sonia and Luigi Miragoli and Luca Venturi and Fabio Tedoldi",

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T1 - Hyperpolarized esters as metabolic markers in mr

AU - Jensen, Pernille Rose

AU - Lerche, Mathilde Hauge

AU - Karlsson, Magnus

AU - Cabella, Claudia

AU - Colombo Serra, Sonia

AU - Miragoli, Luigi

AU - Venturi, Luca

AU - Tedoldi, Fabio

N1 - Also published as: WO2014118258 (A1) US2015374854 (A1) KR20150111353 (A) JP2016504945 (A) CN104981256 (A)

PY - 2015/12/9

Y1 - 2015/12/9

N2 - The invention relates to a method of Magnetic Resonance (MR) detection, in particular 13C-MR detection, by using a diagnostic medium comprising a hyperpolarized ester, in particular ethyl acetoacetate. The method comprises the detection of the MR signal of a hyperpolarized 13C carboxylic ester and of its respective hyperpolarized metabolite.

AB - The invention relates to a method of Magnetic Resonance (MR) detection, in particular 13C-MR detection, by using a diagnostic medium comprising a hyperpolarized ester, in particular ethyl acetoacetate. The method comprises the detection of the MR signal of a hyperpolarized 13C carboxylic ester and of its respective hyperpolarized metabolite.

M3 - Patent

M1 - EP2950826

Y2 - 2015/12/09

ER -

Hyperpolarized esters as metabolic markers in mr

Abstract

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