Hyperpolarized esters as metabolic markers in mr

Pernille Rose Jensen (Inventor), Mathilde Hauge Lerche (Inventor), Magnus Karlsson (Inventor), Claudia Cabella (Inventor), Sonia Colombo Serra (Inventor), Luigi Miragoli (Inventor), Luca Venturi (Inventor), Fabio Tedoldi (Inventor)

Research output: Patent

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Abstract

The invention relates to a method of Magnetic Resonance (MR) detection, in particular 13C-MR detection, by using a diagnostic medium comprising a hyperpolarized ester, in particular ethyl acetoacetate. The method comprises the detection of the MR signal of a hyperpolarized 13C carboxylic ester and of its respective hyperpolarized metabolite.
Original languageEnglish
IPCA61K 49/ 10 A I
Patent numberEP2950826
Filing date09/12/2015
CountryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date30/01/2014
Priority numberEP20140704304
Publication statusPublished - 9 Dec 2015
Externally publishedYes

Bibliographical note

Also published as: WO2014118258 (A1) US2015374854 (A1) KR20150111353 (A) JP2016504945 (A) CN104981256 (A)

Cite this

Jensen, P. R., Lerche, M. H., Karlsson, M., Cabella, C., Colombo Serra, S., Miragoli, L., Venturi, L., & Tedoldi, F. (2015). IPC No. A61K 49/ 10 A I. Hyperpolarized esters as metabolic markers in mr. (Patent No. EP2950826).