Hyaluronan and phospholipids in boundary lubrication

Chao Liu; Min Wang; Junxue An; Esben Thormann; Andra Dedinaite

doi:10.1039/c2sm26615f

Hyaluronan and phospholipids in boundary lubrication

Chao Liu, Min Wang, Junxue An, Esben Thormann, Andra Dedinaite

KTH Royal Institute of Technology

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Hyaluronan has been found to play an important role in boundary lubrication in joints, but model experiments have shown that free hyaluronan is reluctant to stay between surfaces. We show that hyaluronan, when assisted by a phospholipid bilayer, can act as a boundary lubricant, even at pressures well above those leading to breakdown of cartilage. © The Royal Society of Chemistry 2012.

Original language	English
Journal	Soft Matter
Volume	8
Issue number	40
Pages (from-to)	10241-10244
ISSN	1744-683x
DOIs	https://doi.org/10.1039/c2sm26615f
Publication status	Published - 2012
Externally published	Yes

Keywords

Chemistry
Materials science
Phospholipids

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10.1039/c2sm26615f

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title = "Hyaluronan and phospholipids in boundary lubrication",

abstract = "Hyaluronan has been found to play an important role in boundary lubrication in joints, but model experiments have shown that free hyaluronan is reluctant to stay between surfaces. We show that hyaluronan, when assisted by a phospholipid bilayer, can act as a boundary lubricant, even at pressures well above those leading to breakdown of cartilage. {\textcopyright} The Royal Society of Chemistry 2012.",

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AU - Liu, Chao

AU - Wang, Min

AU - An, Junxue

AU - Thormann, Esben

AU - Dedinaite, Andra

PY - 2012

Y1 - 2012

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AB - Hyaluronan has been found to play an important role in boundary lubrication in joints, but model experiments have shown that free hyaluronan is reluctant to stay between surfaces. We show that hyaluronan, when assisted by a phospholipid bilayer, can act as a boundary lubricant, even at pressures well above those leading to breakdown of cartilage. © The Royal Society of Chemistry 2012.

KW - Chemistry

KW - Materials science

KW - Phospholipids

U2 - 10.1039/c2sm26615f

DO - 10.1039/c2sm26615f

M3 - Journal article

SN - 1744-683x

VL - 8

SP - 10241

EP - 10244

JO - Soft Matter

JF - Soft Matter

IS - 40

ER -

Hyaluronan and phospholipids in boundary lubrication

Abstract

Keywords

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