Hyaluronan and phospholipids in boundary lubrication

Chao Liu, Min Wang, Junxue An, Esben Thormann, Andra Dedinaite

Research output: Contribution to journalJournal articleResearchpeer-review


Hyaluronan has been found to play an important role in boundary lubrication in joints, but model experiments have shown that free hyaluronan is reluctant to stay between surfaces. We show that hyaluronan, when assisted by a phospholipid bilayer, can act as a boundary lubricant, even at pressures well above those leading to breakdown of cartilage. © The Royal Society of Chemistry 2012.
Original languageEnglish
JournalSoft Matter
Issue number40
Pages (from-to)10241-10244
Publication statusPublished - 2012
Externally publishedYes


  • Chemistry
  • Materials science
  • Phospholipids


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