Human In-vivo Brain MR Current Density Imaging (MRCDI) based on Steady-state Free Precession Free Induction Decay (SSFP-FID)

Cihan Göksu; Lars G.  Hanson; Hartwig Siebner; Philipp Ehses; Klaus Scheffler; Axel Thielscher

Human In-vivo Brain MR Current Density Imaging (MRCDI) based on Steady-state Free Precession Free Induction Decay (SSFP-FID)

Cihan Göksu
, Lars G. Hanson
, Hartwig Siebner
, Philipp Ehses
, Klaus Scheffler
, Axel Thielscher

Copenhagen University Hospital Herlev and Gentofte
University of Tübingen

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

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Abstract

MRCDI is a novel technique for non-invasive measurement of weak currents in the human head, which is important in several neuroscience applications. Here, we present reliable in-vivo MRCDI measurements in the human brain based on SSFP-FID, yielding an unprecedented accuracy. We demonstrate the destructive influences of stray magnetic fields caused by the current passing through feeding cables, and propose a correction method. Also, we show inter-individual differences in MRCDI measurements for two different current proles, and compare the measurements with simulations based on individualized head models. The simulations of the current-induced magnetic fields show good agreement with in-vivo brain measurements.

Original language	English
Publication date	2018
Number of pages	3
Publication status	Published - 2018
Event	Joint Annual Meeting ISMRM-ESMRMB 2018 - Paris Expo Porte de Versailles, Paris, France Duration: 16 Jun 2018 → 21 Jun 2018 https://www.ismrm.org/18m/

Conference

Conference	Joint Annual Meeting ISMRM-ESMRMB 2018
Location	Paris Expo Porte de Versailles
Country/Territory	France
City	Paris
Period	16/06/2018 → 21/06/2018
Internet address	https://www.ismrm.org/18m/

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@conference{8336485ff10d4403852740a0ec2cab3c,

title = "Human In-vivo Brain MR Current Density Imaging (MRCDI) based on Steady-state Free Precession Free Induction Decay (SSFP-FID)",

abstract = "MRCDI is a novel technique for non-invasive measurement of weak currents in the human head, which is important in several neuroscience applications. Here, we present reliable in-vivo MRCDI measurements in the human brain based on SSFP-FID, yielding an unprecedented accuracy. We demonstrate the destructive influences of stray magnetic fields caused by the current passing through feeding cables, and propose a correction method. Also, we show inter-individual differences in MRCDI measurements for two different current proles, and compare the measurements with simulations based on individualized head models. The simulations of the current-induced magnetic fields show good agreement with in-vivo brain measurements. ",

author = "Cihan G{\"o}ksu and Hanson, \{Lars G.\} and Hartwig Siebner and Philipp Ehses and Klaus Scheffler and Axel Thielscher",

year = "2018",

language = "English",

note = "Joint Annual Meeting ISMRM-ESMRMB 2018 ; Conference date: 16-06-2018 Through 21-06-2018",

url = "https://www.ismrm.org/18m/",

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Human In-vivo Brain MR Current Density Imaging (MRCDI) based on Steady-state Free Precession Free Induction Decay (SSFP-FID). / Göksu, Cihan; Hanson, Lars G. ; Siebner, Hartwig et al.
2018. Abstract from Joint Annual Meeting ISMRM-ESMRMB 2018, Paris, France.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

TY - ABST

T1 - Human In-vivo Brain MR Current Density Imaging (MRCDI) based on Steady-state Free Precession Free Induction Decay (SSFP-FID)

AU - Göksu, Cihan

AU - Hanson, Lars G.

AU - Siebner, Hartwig

AU - Ehses, Philipp

AU - Scheffler, Klaus

AU - Thielscher, Axel

PY - 2018

Y1 - 2018

N2 - MRCDI is a novel technique for non-invasive measurement of weak currents in the human head, which is important in several neuroscience applications. Here, we present reliable in-vivo MRCDI measurements in the human brain based on SSFP-FID, yielding an unprecedented accuracy. We demonstrate the destructive influences of stray magnetic fields caused by the current passing through feeding cables, and propose a correction method. Also, we show inter-individual differences in MRCDI measurements for two different current proles, and compare the measurements with simulations based on individualized head models. The simulations of the current-induced magnetic fields show good agreement with in-vivo brain measurements.

AB - MRCDI is a novel technique for non-invasive measurement of weak currents in the human head, which is important in several neuroscience applications. Here, we present reliable in-vivo MRCDI measurements in the human brain based on SSFP-FID, yielding an unprecedented accuracy. We demonstrate the destructive influences of stray magnetic fields caused by the current passing through feeding cables, and propose a correction method. Also, we show inter-individual differences in MRCDI measurements for two different current proles, and compare the measurements with simulations based on individualized head models. The simulations of the current-induced magnetic fields show good agreement with in-vivo brain measurements.

M3 - Conference abstract for conference

T2 - Joint Annual Meeting ISMRM-ESMRMB 2018

Y2 - 16 June 2018 through 21 June 2018

ER -

Human In-vivo Brain MR Current Density Imaging (MRCDI) based on Steady-state Free Precession Free Induction Decay (SSFP-FID)

Abstract

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