How compelling are the data for Epstein-Barr virus being a trigger for systemic lupus and other autoimmune diseases?

Anette Draborg, Jose Maria Gonzalez-Izarzugaza, Gunnar Houen

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    Abstract

    Systemic lupus erythematosus (SLE) is caused by a combination of genetic and acquired immunodeficiencies and environmental factors including infections. An association with Epstein-Barr virus (EBV) has been established by numerous studies over the past decades. Here, we review recent experimental studies on EBV, and present our integrated theory of SLE development.
    Original languageEnglish
    JournalCurrent Opinion in Rheumatology
    Volume28
    Issue number4
    Pages (from-to)398-404
    ISSN1040-8711
    DOIs
    Publication statusPublished - 2016

    Keywords

    • EBV
    • Infections
    • Immuno-deficiencies
    • SLE

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