Holistic Capacity Management and Production Planning in the Pharmaceutical Supply Chain

Simon B. Lindahl, Deenesh K. Babi, Krist V. Gernaey, Gürkan Sin*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Abstract

Pharmaceutical companies are responsible for the consistent delivery of life-saving medicines to patients. Production must be planned to ensure supply-demand balancing and time-dependent capacity constraints must be handled through capacity planning. This work describes an aggregated 4-step framework for mid-term decision support on integrated production and capacity planning including the relevant MILP mathematical models. The framework has been developed by combining theory with observed requirements in industry and it is applied to a case study abstracted from industrial API manufacturing to provide an example of its industrial relevance.
Original languageEnglish
Title of host publication32nd European Symposium on Computer Aided Process Engineering
EditorsLudovic Montastruc, Stephane Negny
Volume51
Place of PublicationAmsterdam
PublisherElsevier
Publication date2022
Pages925-930
ISBN (Electronic)978-0-443-18631-8, 978-0-323-95879-0
DOIs
Publication statusPublished - 2022
Event32nd European Symposium on Computer Aided Process Engineering - Toulouse, France
Duration: 12 Jun 202215 Jun 2022

Conference

Conference32nd European Symposium on Computer Aided Process Engineering
Country/TerritoryFrance
CityToulouse
Period12/06/202215/06/2022
SeriesComputer Aided Chemical Engineering
Volume51
ISSN1570-7946

Keywords

  • MILP
  • Planning & Scheduling
  • Pharmaceutical Manufacturing
  • Capacity Planning

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