Histidine methyltransferase for increased peptide and protein stability

Jonas Laurberg Simonsen (Inventor), Cristina Hernández Rollán (Inventor), Jakob Blæsbjerg Hoof (Inventor), Morten Helge Hauberg Nørholm (Inventor), Tanveer Signh Batth (Inventor), Jesper Velgaard Olsen (Inventor), Katja Salomon Johansen (Inventor), Søren Brander (Inventor)

Research output: Patent

6 Downloads (Pure)

Abstract

The present invention relates to an enzyme exhibiting histidine N-methyltransferase activity, a microbial cell comprising a gene encoding such enzyme, and use of this enzyme for producing a target peptide or protein having a methylated N-terminal histidine residue.

Original languageEnglish
IPCC12N 15/ 80 A I
Patent numberWO2023194390
Filing date08/04/2022
Country/TerritoryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date08/04/2022
Priority numberEP20220167491
Publication statusPublished - 12 Oct 2023

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