High-speed counting and sizing of cells in an impedance flow microcytometer with compact electronic instrumentation

Oscar Castillo-Fernandez, Romén Rodriguez-Trujíllo, Gabriel Gomila, Josep Samitier

    Research output: Contribution to journalJournal articleResearchpeer-review

    Abstract

    Here we describe a high-throughput impedance flow cytometer on a chip. This device was built using compact and inexpensive electronic instrumentation. The system was used to count and size a mixed cell sample containing red blood cells and white blood cells. It demonstrated a counting capacity of up to ~500 counts/s and was validated through a synchronised high-speed optical detection system. In addition, the device showed excellent discrimination performance under high-throughput conditions.
    Original languageEnglish
    JournalMicrofluidics and Nanofluidics
    Volume16
    Issue number1-2
    Pages (from-to)91-99
    ISSN1613-4982
    DOIs
    Publication statusPublished - 2014

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