High Diversity of Extended-Spectrum β-Lactamases in Escherichia coli Isolates from Italian Broiler Flocks

Valeria Bortolaia, Luca Guardabassi, Marcello Trevisani, Magne Bisgaard, Luciano Venturi, Anders Miki Bojesen

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Abstract

We characterized 67 Escherichia coli isolates with reduced susceptibility to cefotaxime or ceftiofur obtained from healthy broilers housed in five Italian farms. The blaCTX-M-1, blaCTX-M-32 and blaSHV-12 β-lactamase genes were identified on IncI1, IncN, or IncFIB plasmids. Considerable genetic diversity was detected among the extended-spectrum β-lactamase (ESBL)-producing isolates, and we identified indistinguishable strains in unrelated farms and indistinguishable plasmids in genetically unrelated strains. The detection of highly mobile plasmids suggests a potential animal reservoir for β-lactamase genes.
Original languageEnglish
JournalAntimicrobial Agents and Chemotherapy
Volume54
Issue number4
Pages (from-to)1623-1626
Number of pages4
ISSN0066-4804
Publication statusPublished - 2010
Externally publishedYes

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