High-affinity human leucocyte antigen class I binding variola-derived peptides induce CD4(+) T cell responses more than 30 years post-vaccinia virus vaccination

M. Wang; Sheila Tuyet Tang; Ole Lund; M. H. Dziegiel; S. Buus; M. H. Claesson

doi:10.1111/j.1365-2249.2008.03856.x

High-affinity human leucocyte antigen class I binding variola-derived peptides induce CD4(+) T cell responses more than 30 years post-vaccinia virus vaccination

M. Wang, Sheila Tuyet Tang, Ole Lund, M. H. Dziegiel, S. Buus, M. H. Claesson

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Interferon-gamma secreting T lymphocytes against pox virus-derived synthetic 9-mer peptides were tested by enzyme-linked immunospot in peripheral blood of individuals vaccinated with vaccinia virus more than 30 years ago. The peptides were characterized biochemically as high-affinity human leucocyte antigen (HLA) class I binders (K-D

Original language	English
Journal	Clinical and Experimental Immunology
Volume	155
Issue number	3
Pages (from-to)	441-446
ISSN	0009-9104
DOIs	https://doi.org/10.1111/j.1365-2249.2008.03856.x
Publication status	Published - 2009

Keywords

smallpox virus
HLA class II
peptide
vaccine
HLA class I

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title = "High-affinity human leucocyte antigen class I binding variola-derived peptides induce CD4(+) T cell responses more than 30 years post-vaccinia virus vaccination",

abstract = "Interferon-gamma secreting T lymphocytes against pox virus-derived synthetic 9-mer peptides were tested by enzyme-linked immunospot in peripheral blood of individuals vaccinated with vaccinia virus more than 30 years ago. The peptides were characterized biochemically as high-affinity human leucocyte antigen (HLA) class I binders (K-D ",

keywords = "smallpox virus, HLA class II, peptide, vaccine, HLA class I",

author = "M. Wang and Tang, {Sheila Tuyet} and Ole Lund and Dziegiel, {M. H.} and S. Buus and Claesson, {M. H.}",

year = "2009",

doi = "10.1111/j.1365-2249.2008.03856.x",

language = "English",

volume = "155",

pages = "441--446",

journal = "Clinical and Experimental Immunology",

issn = "0009-9104",

publisher = "Wiley-Blackwell",

number = "3",

}

High-affinity human leucocyte antigen class I binding variola-derived peptides induce CD4(+) T cell responses more than 30 years post-vaccinia virus vaccination. / Wang, M.; Tang, Sheila Tuyet; Lund, Ole; Dziegiel, M. H.; Buus, S.; Claesson, M. H.

In: Clinical and Experimental Immunology, Vol. 155, No. 3, 2009, p. 441-446.

Research output: Contribution to journal › Journal article › Research › peer-review

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T1 - High-affinity human leucocyte antigen class I binding variola-derived peptides induce CD4(+) T cell responses more than 30 years post-vaccinia virus vaccination

AU - Wang, M.

AU - Tang, Sheila Tuyet

AU - Lund, Ole

AU - Dziegiel, M. H.

AU - Buus, S.

AU - Claesson, M. H.

PY - 2009

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AB - Interferon-gamma secreting T lymphocytes against pox virus-derived synthetic 9-mer peptides were tested by enzyme-linked immunospot in peripheral blood of individuals vaccinated with vaccinia virus more than 30 years ago. The peptides were characterized biochemically as high-affinity human leucocyte antigen (HLA) class I binders (K-D

KW - smallpox virus

KW - HLA class II

KW - peptide

KW - vaccine

KW - HLA class I

U2 - 10.1111/j.1365-2249.2008.03856.x

DO - 10.1111/j.1365-2249.2008.03856.x

M3 - Journal article

VL - 155

SP - 441

EP - 446

JO - Clinical and Experimental Immunology

JF - Clinical and Experimental Immunology

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