Hierarchical organization in aggregates of protein molecules

Henrik Bohr; Anders Kyhle; Alexis Hammer Sørensen; Jakob Bohr

doi:10.1007/s004600050265

Hierarchical organization in aggregates of protein molecules

Henrik Bohr, Anders Kyhle, Alexis Hammer Sørensen, Jakob Bohr

Department of Physics

Research output: Contribution to journal › Conference article › Research › peer-review

Abstract

The aggregation of proteins into small clusters is studied by atomic force and electron microscopy. Scaling laws and fractal behaviour in the growth of the aggregates and in the correlation between aggregates is seen. A phase diagram of the aggregation process where the protonic concentration of the solution and the density of protein are varied shows the existence of specific growth processes resulting in different branch-like structures. The resulting structures are strongly influenced by the shape of each protein molecule. Lysozyme and ribonuclease are found to form spherical structures with a narrow size distribution.

Original language	English
Journal	Zeitschrift fur Physik D-Atoms Molecules and Clusters
Volume	40
Issue number	1-4
Pages (from-to)	513-515
ISSN	0178-7683
DOIs	https://doi.org/10.1007/s004600050265
Publication status	Published - 1997
Event	8th International Symposium on Small Particles and Inorganic Clusters - Copenhagen, Denmark Duration: 1 Jul 1996 → 6 Jul 1996 Conference number: 8 http://www.springer.com/physics/atomic,+molecular,+optical+%26+plasma+physics/book/978-3-642-64586-0

Conference

Conference	8th International Symposium on Small Particles and Inorganic Clusters
Number	8
Country/Territory	Denmark
City	Copenhagen
Period	01/07/1996 → 06/07/1996
Internet address	http://www.springer.com/physics/atomic,+molecular,+optical+%26+plasma+physics/book/978-3-642-64586-0

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title = "Hierarchical organization in aggregates of protein molecules",

abstract = "The aggregation of proteins into small clusters is studied by atomic force and electron microscopy. Scaling laws and fractal behaviour in the growth of the aggregates and in the correlation between aggregates is seen. A phase diagram of the aggregation process where the protonic concentration of the solution and the density of protein are varied shows the existence of specific growth processes resulting in different branch-like structures. The resulting structures are strongly influenced by the shape of each protein molecule. Lysozyme and ribonuclease are found to form spherical structures with a narrow size distribution. ",

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year = "1997",

doi = "10.1007/s004600050265",

language = "English",

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journal = "Zeitschrift fur Physik D-Atoms Molecules and Clusters",

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AU - Bohr, Henrik

AU - Kyhle, Anders

AU - Sørensen, Alexis Hammer

AU - Bohr, Jakob

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PY - 1997

Y1 - 1997

N2 - The aggregation of proteins into small clusters is studied by atomic force and electron microscopy. Scaling laws and fractal behaviour in the growth of the aggregates and in the correlation between aggregates is seen. A phase diagram of the aggregation process where the protonic concentration of the solution and the density of protein are varied shows the existence of specific growth processes resulting in different branch-like structures. The resulting structures are strongly influenced by the shape of each protein molecule. Lysozyme and ribonuclease are found to form spherical structures with a narrow size distribution.

AB - The aggregation of proteins into small clusters is studied by atomic force and electron microscopy. Scaling laws and fractal behaviour in the growth of the aggregates and in the correlation between aggregates is seen. A phase diagram of the aggregation process where the protonic concentration of the solution and the density of protein are varied shows the existence of specific growth processes resulting in different branch-like structures. The resulting structures are strongly influenced by the shape of each protein molecule. Lysozyme and ribonuclease are found to form spherical structures with a narrow size distribution.

U2 - 10.1007/s004600050265

DO - 10.1007/s004600050265

M3 - Conference article

VL - 40

SP - 513

EP - 515

JO - Zeitschrift fur Physik D-Atoms Molecules and Clusters

JF - Zeitschrift fur Physik D-Atoms Molecules and Clusters

SN - 0178-7683

IS - 1-4

T2 - 8th International Symposium on Small Particles and Inorganic Clusters

Y2 - 1 July 1996 through 6 July 1996

ER -

Hierarchical organization in aggregates of protein molecules

Abstract

Conference

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