Abstract
In this chapter the role of electron transfer in determining the
behaviour of the ATP synthesising enzyme in E. coli is analysed.
It is concluded that the latter enzyme lacks control because of
special properties of the electron transfer components. These
properties range from absence of a strong back pressure by the
protonmotive force on the rate of electron transfer to
hierarchical regulation of the expression of the gens that encode
the electron transfer proteins as a response to changes in the
bioenergetic properties of the cell.The discussion uses
Hierarchical Control Analysis as a paradigm. This allows one to
analyse a complex system of regulatory interactions in terms of
the importance of the contributing factors.
| Original language | English |
|---|---|
| Title of host publication | Biological Electron-transfer chains: genetics, composition and mode of operation |
| Place of Publication | The Netherlands |
| Publisher | Kluwer Academic Publishers - Nato series |
| Publication date | 1997 |
| Publication status | Published - 1997 |