TY - JOUR
T1 - Hamigerone and Dihydrohamigerone: Two Acetate derived, antifungal metabolites from Hamigera avellanea.
AU - Breinholt, Jens
AU - Kjær, Anders
AU - Olsen, Carl Erik
AU - Rassing, Birgitte R.
AU - Rosendahl, Connie N.
PY - 1997
Y1 - 1997
N2 - The fungus Hamigera avellanea is found to be the source of two metabolites, hamigerone (C25H32O5) and dihydrohamigerone (C25H34O5), the former exhibiting in vitro growth inhibitory activity against phytopathogenic fungi. Their chemical structures and configurations, save for details related to the stereochemistry, have been established by a variety of spectroscopic techniques. Feeding the fungus with specifically labelled 13C-precursors served to establish the biosynthetic derivation of the two metabolites from ten intact acetate and five methioninederived C1-units.
AB - The fungus Hamigera avellanea is found to be the source of two metabolites, hamigerone (C25H32O5) and dihydrohamigerone (C25H34O5), the former exhibiting in vitro growth inhibitory activity against phytopathogenic fungi. Their chemical structures and configurations, save for details related to the stereochemistry, have been established by a variety of spectroscopic techniques. Feeding the fungus with specifically labelled 13C-precursors served to establish the biosynthetic derivation of the two metabolites from ten intact acetate and five methioninederived C1-units.
U2 - 10.3891/acta.chem.scand.51-1241
DO - 10.3891/acta.chem.scand.51-1241
M3 - Journal article
SN - 0904-213X
VL - 51
SP - 1241
EP - 1244
JO - Acta Chemica Scandinavica
JF - Acta Chemica Scandinavica
IS - 12
ER -