The alleviation of glucose control of maltose metabolism brought about by MIG1 disruption was compared to that by MAL overexpression in a haploid Saccharomyces cerevisiae strain. The sugar consumption profiles during cultivation of the wild type, single transformants and a double transformant in a mixed glucose-maltose medium revealed that the MAL-constitutive strains were more alleviated than the single MIG1-disrupted transformant. While all transformants exhibited higher maximum specific growth rates (0.24-0.25 h(-1)) in glucose-maltose mixtures than the wild type strain (0.20 h(-1)), the MAL-constitutive transformants grew even faster (0.27-0.30 h(-1)) in pure glucose medium than the wild type strain (0.24 h(-1)).
|Journal||Food Technology and Biotechnology|
|Publication status||Published - 1997|
|Event||Meeting on Yeast Nutrition and Natural Habitats at the 18th International Specialised Symposium on Yeast (ISSY) - Bled, Slovenia|
Duration: 24 Aug 1997 → 29 Aug 1997
Conference number: 18
|Conference||Meeting on Yeast Nutrition and Natural Habitats at the 18th International Specialised Symposium on Yeast (ISSY)|
|Period||24/08/1997 → 29/08/1997|
- Saccharomyces cerevisiae
- baker's yeast
- glucose repression
- catabolite inactivation
- genetic engineering
Klein, C., Olsson, L., Rønnow, B., Mikkelsen, J. D., & Nielsen, J. B. (1997). Glucose and maltose metabolism in MIG1-disrupted and MAL-constitutive strains of Saccharomyces cerevisiae. Food Technology and Biotechnology, 35(4), 287-292.