Glucocorticoids Exert a Dual Role in B-Cell Acute Lymphoblastic Leukemia: Apoptosis and Differentiation of Early B-Cell Populations

Jolando Sarno, Christina Pedersen, Astrea Jager, Tyler Burns, Giuseppe Gaipa, Garry Nolan, Alessio Bava, Kara Davis

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Abstract

Glucocorticoids (GCs) are routinely administered for B-cell acute lymphoblastic leukemia (BCP-ALL) treatment and the response to glucocorticoids is considered a strong prognostic marker of relapse risk. Despite this, their mechanism of action and resistance are still poorly understood.
Original languageEnglish
Article number3157
JournalExperimental Hematology. Supplement
Volume64
Issue numberSupp
Pages (from-to)S100
ISSN0256-9280
DOIs
Publication statusPublished - 2018

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