Getting to grips with endoscopy - Learning endoscopic surgical skills induces bi-hemispheric plasticity of the grasping network

Anke Ninija Karabanov*, Friederike Irmen, Kristoffer Hougaard Madsen, Brian Numelin Haagensen, Svend Schulze, Thue Bisgaard, Hartwig Roman Siebner

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Endoscopic surgery requires skilled bimanual use of complex instruments that extend the peri-personal workspace. To delineate brain structures involved in learning such surgical skills, 48 medical students without surgical experience were randomly assigned to five training sessions on a virtual-reality endoscopy simulator or to a non-training group. Brain activity was probed with functional MRI while participants performed endoscopic tasks. Repeated task performance in the scanner was sufficient to enhance task-related activity in left ventral premotor cortex (PMv) and the anterior Intraparietal Sulcus (aIPS). Simulator training induced additional increases in task-related activation in right PMv and aIPS and reduced effective connectivity from left to right PMv. Skill improvement after training scaled with stronger task-related activation of the lateral left primary motor hand area (M1-HAND). The results suggest that a bilateral fronto-parietal grasping network and left M1-HAND are engaged in bimanual learning of tool-based manipulations in an extended peri-personal space.
Original languageEnglish
JournalNeuroImage
Volume189
Pages (from-to)32-44
Number of pages13
ISSN1053-8119
DOIs
Publication statusPublished - 2019

Keywords

  • Bimanual skill learning
  • Endoscopic surgery
  • Fronto-parietal grasping network
  • Grasping network

Cite this

Karabanov, Anke Ninija ; Irmen, Friederike ; Madsen, Kristoffer Hougaard ; Haagensen, Brian Numelin ; Schulze, Svend ; Bisgaard, Thue ; Siebner, Hartwig Roman. / Getting to grips with endoscopy - Learning endoscopic surgical skills induces bi-hemispheric plasticity of the grasping network. In: NeuroImage. 2019 ; Vol. 189. pp. 32-44.
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abstract = "Endoscopic surgery requires skilled bimanual use of complex instruments that extend the peri-personal workspace. To delineate brain structures involved in learning such surgical skills, 48 medical students without surgical experience were randomly assigned to five training sessions on a virtual-reality endoscopy simulator or to a non-training group. Brain activity was probed with functional MRI while participants performed endoscopic tasks. Repeated task performance in the scanner was sufficient to enhance task-related activity in left ventral premotor cortex (PMv) and the anterior Intraparietal Sulcus (aIPS). Simulator training induced additional increases in task-related activation in right PMv and aIPS and reduced effective connectivity from left to right PMv. Skill improvement after training scaled with stronger task-related activation of the lateral left primary motor hand area (M1-HAND). The results suggest that a bilateral fronto-parietal grasping network and left M1-HAND are engaged in bimanual learning of tool-based manipulations in an extended peri-personal space.",
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author = "Karabanov, {Anke Ninija} and Friederike Irmen and Madsen, {Kristoffer Hougaard} and Haagensen, {Brian Numelin} and Svend Schulze and Thue Bisgaard and Siebner, {Hartwig Roman}",
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Getting to grips with endoscopy - Learning endoscopic surgical skills induces bi-hemispheric plasticity of the grasping network. / Karabanov, Anke Ninija; Irmen, Friederike; Madsen, Kristoffer Hougaard; Haagensen, Brian Numelin; Schulze, Svend; Bisgaard, Thue; Siebner, Hartwig Roman.

In: NeuroImage, Vol. 189, 2019, p. 32-44.

Research output: Contribution to journalJournal articleResearchpeer-review

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T1 - Getting to grips with endoscopy - Learning endoscopic surgical skills induces bi-hemispheric plasticity of the grasping network

AU - Karabanov, Anke Ninija

AU - Irmen, Friederike

AU - Madsen, Kristoffer Hougaard

AU - Haagensen, Brian Numelin

AU - Schulze, Svend

AU - Bisgaard, Thue

AU - Siebner, Hartwig Roman

PY - 2019

Y1 - 2019

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AB - Endoscopic surgery requires skilled bimanual use of complex instruments that extend the peri-personal workspace. To delineate brain structures involved in learning such surgical skills, 48 medical students without surgical experience were randomly assigned to five training sessions on a virtual-reality endoscopy simulator or to a non-training group. Brain activity was probed with functional MRI while participants performed endoscopic tasks. Repeated task performance in the scanner was sufficient to enhance task-related activity in left ventral premotor cortex (PMv) and the anterior Intraparietal Sulcus (aIPS). Simulator training induced additional increases in task-related activation in right PMv and aIPS and reduced effective connectivity from left to right PMv. Skill improvement after training scaled with stronger task-related activation of the lateral left primary motor hand area (M1-HAND). The results suggest that a bilateral fronto-parietal grasping network and left M1-HAND are engaged in bimanual learning of tool-based manipulations in an extended peri-personal space.

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