Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome

Louise Ramhøj; Sofie Frank Rising; Bertrand Evrard; Frédéric Chalmel; Terje Svingen

Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome

Louise Ramhøj^*
, Sofie Frank Rising
, Bertrand Evrard
, Frédéric Chalmel
, Terje Svingen

^*Corresponding author for this work

Université de Rennes

Research output: Contribution to conference › Poster › Research › peer-review

Abstract

Thyroperoxidase (TPO) inhibiting medical drugs and environmental chemicals can cause thyroid hormone (TH) system disruption with adverse consequences to TH-dependent processes in the developing brain and other tissues. Here we investigated the effects of methimazole (MMI) and amitrole on the developing fetal and postnatal thyroid gland.

Original language	English
Publication date	2025
Number of pages	1
Publication status	Published - 2025
Event	17th International Thyroid Congress - Rio de Janeiro Duration: 18 Jun 2025 → 22 Jun 2025

Conference

Conference	17th International Thyroid Congress
City	Rio de Janeiro
Period	18/06/2025 → 22/06/2025

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Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome
Ramhøj, L., Rising, S. F., Evrard, B., Chalmel, F. & Svingen, T., 2025. 1 p.
Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Cite this

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title = "Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome",

abstract = "Thyroperoxidase (TPO) inhibiting medical drugs and environmental chemicals can cause thyroid hormone (TH) system disruption with adverse consequences to TH-dependent processes in the developing brain and other tissues. Here we investigated the effects of methimazole (MMI) and amitrole on the developing fetal and postnatal thyroid gland.",

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TY - CONF

T1 - Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome

AU - Ramhøj, Louise

AU - Rising, Sofie Frank

AU - Evrard, Bertrand

AU - Chalmel, Frédéric

AU - Svingen, Terje

PY - 2025

Y1 - 2025

N2 - Thyroperoxidase (TPO) inhibiting medical drugs and environmental chemicals can cause thyroid hormone (TH) system disruption with adverse consequences to TH-dependent processes in the developing brain and other tissues. Here we investigated the effects of methimazole (MMI) and amitrole on the developing fetal and postnatal thyroid gland.

AB - Thyroperoxidase (TPO) inhibiting medical drugs and environmental chemicals can cause thyroid hormone (TH) system disruption with adverse consequences to TH-dependent processes in the developing brain and other tissues. Here we investigated the effects of methimazole (MMI) and amitrole on the developing fetal and postnatal thyroid gland.

M3 - Poster

T2 - 17th International Thyroid Congress

Y2 - 18 June 2025 through 22 June 2025

ER -

Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome

Abstract

Conference

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Research output

Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome

Cite this