Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome

Louise Ramhøj; Sofie Frank Rising; Bertrand Evrard; Frédéric Chalmel; Terje Svingen

Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome

Louise Ramhøj
, Sofie Frank Rising
, Bertrand Evrard
, Frédéric Chalmel
, Terje Svingen

Université de Rennes

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

Abstract

Thyroid hormone system-disrupting compounds can cause developmental hypothyroidism, adversely affecting thyroid hormone-dependent processes, including brain development. Inhibition of thyroperoxidase (TPO) in the thyroid gland is a key mechanism leading to such adverse effects, but the direct impact on the developing thyroid gland remains insufficiently characterized, not least at the transcriptional level.

Original language	English
Publication date	2025
Number of pages	1
Publication status	Published - 2025
Event	17th International Thyroid Congress - Rio de Janeiro Duration: 18 Jun 2025 → 22 Jun 2025

Conference

Conference	17th International Thyroid Congress
City	Rio de Janeiro
Period	18/06/2025 → 22/06/2025

OpenUrl availability

Full text

Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome
Ramhøj, L., Rising, S. F., Evrard, B., Chalmel, F. & Svingen, T., 2025. 1 p.
Research output: Contribution to conference › Poster › Research › peer-review

Cite this

@conference{667eabbee7114805add522008be62ecb,

title = "Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome",

abstract = "Thyroid hormone system-disrupting compounds can cause developmental hypothyroidism, adversely affecting thyroid hormone-dependent processes, including brain development. Inhibition of thyroperoxidase (TPO) in the thyroid gland is a key mechanism leading to such adverse effects, but the direct impact on the developing thyroid gland remains insufficiently characterized, not least at the transcriptional level.",

author = "Louise Ramh{\o}j and Rising, \{Sofie Frank\} and Bertrand Evrard and Fr{\'e}d{\'e}ric Chalmel and Terje Svingen",

year = "2025",

language = "English",

note = "17th International Thyroid Congress, ITC 2025 ; Conference date: 18-06-2025 Through 22-06-2025",

}

Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome. / Ramhøj, Louise; Rising, Sofie Frank; Evrard, Bertrand et al.
2025. Abstract from 17th International Thyroid Congress, Rio de Janeiro.

Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

TY - ABST

T1 - Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome

AU - Ramhøj, Louise

AU - Rising, Sofie Frank

AU - Evrard, Bertrand

AU - Chalmel, Frédéric

AU - Svingen, Terje

PY - 2025

Y1 - 2025

N2 - Thyroid hormone system-disrupting compounds can cause developmental hypothyroidism, adversely affecting thyroid hormone-dependent processes, including brain development. Inhibition of thyroperoxidase (TPO) in the thyroid gland is a key mechanism leading to such adverse effects, but the direct impact on the developing thyroid gland remains insufficiently characterized, not least at the transcriptional level.

AB - Thyroid hormone system-disrupting compounds can cause developmental hypothyroidism, adversely affecting thyroid hormone-dependent processes, including brain development. Inhibition of thyroperoxidase (TPO) in the thyroid gland is a key mechanism leading to such adverse effects, but the direct impact on the developing thyroid gland remains insufficiently characterized, not least at the transcriptional level.

M3 - Conference abstract for conference

T2 - 17th International Thyroid Congress

Y2 - 18 June 2025 through 22 June 2025

ER -

Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome

Abstract

Conference

OpenUrl availability

Fingerprint

Research output

Gestational and lactational exposure to thyroperoxidase-inhibiting compounds disrupts the developing thyroid gland transcriptome

Cite this