Genomic evidence for the Pleistocene and recent population history of Native Americans

Maanasa Raghavan, Matthias Steinruecken, Kelley Harris, Stephan Schiffels, Simon Rasmussen, Michael DeGiorgio, Anders Albrechtsen, Cristina Valdiosera, Maria C. Avila-Arcos, Anna-Sapfo Malaspinas, J. Victor Moreno-Mayar, Thorfinn S. Korneliussen, Tracey Pierre, Morten Rasmussen, Paula F. Campos, Peter De Barros Damgaard, Morten E. Allentoft, Andaine Seguin-Orlando, Thomas Stafford, David J. MeltzerEske Willerslev

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    Howand when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericues and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model.
    Original languageEnglish
    Article numberaab3884
    Issue number6250
    Number of pages12
    Publication statusPublished - 2015

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