Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion

Jahir M Gutierrez, Amir Feizi, Shangzhong Li, Thomas B Kallehauge, Hooman Hefzi, Lise Marie Grav, Daniel Ley, Deniz Baycin Hizal, Michael J Betenbaugh, Bjørn Gunnar Voldborg, Helene Faustrup Kildegaard, Gyun Min Lee, Bernhard O Palsson, Jens Nielsen, Nathan E Lewis*

*Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology