Genome-Scale Models

Basti Bergdahl, Nikolaus Sonnenschein, Daniel Machado, Markus Herrgard, Jochen Förster

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Abstract

An introduction to genome-scale models, how to build and use them, will be
given in this chapter. Genome-scale models have become an important part of
systems biology and metabolic engineering, and are increasingly used in research,
both in academica and in industry, both for modeling chemical production and
for fundamental studies aiming at describing and explaining phenotypic behavior
of microbial and mammalian cells.
Original languageEnglish
Title of host publicationFundamental Bioengineering
EditorsJohn Villadsen
Number of pages40
Place of PublicationWeinheim, Germany
PublisherWiley-VCH
Publication date2016
Edition1st edition
Pages143-182
Chapter6
ISBN (Print)9783527336746
ISBN (Electronic)9783527697441
DOIs
Publication statusPublished - 2016
SeriesAdvanced Biotechnology
ISSN2365-3035

Keywords

  • Annotated genome
  • Eukaryotic models
  • Genome-scale models
  • Metabolic networks reconstruction
  • Metabolome
  • Model simulations
  • Proteome
  • Transcriptome

Cite this

Bergdahl, B., Sonnenschein, N., Machado, D., Herrgard, M., & Förster, J. (2016). Genome-Scale Models. In J. Villadsen (Ed.), Fundamental Bioengineering (1st edition ed., pp. 143-182). Weinheim, Germany: Wiley-VCH. Advanced Biotechnology https://doi.org/10.1002/9783527697441.ch06
Bergdahl, Basti ; Sonnenschein, Nikolaus ; Machado, Daniel ; Herrgard, Markus ; Förster, Jochen. / Genome-Scale Models. Fundamental Bioengineering. editor / John Villadsen. 1st edition. ed. Weinheim, Germany : Wiley-VCH, 2016. pp. 143-182 (Advanced Biotechnology).
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Bergdahl, B, Sonnenschein, N, Machado, D, Herrgard, M & Förster, J 2016, Genome-Scale Models. in J Villadsen (ed.), Fundamental Bioengineering. 1st edition edn, Wiley-VCH, Weinheim, Germany, Advanced Biotechnology, pp. 143-182. https://doi.org/10.1002/9783527697441.ch06

Genome-Scale Models. / Bergdahl, Basti; Sonnenschein, Nikolaus; Machado, Daniel; Herrgard, Markus; Förster, Jochen.

Fundamental Bioengineering. ed. / John Villadsen. 1st edition. ed. Weinheim, Germany : Wiley-VCH, 2016. p. 143-182 (Advanced Biotechnology).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

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Bergdahl B, Sonnenschein N, Machado D, Herrgard M, Förster J. Genome-Scale Models. In Villadsen J, editor, Fundamental Bioengineering. 1st edition ed. Weinheim, Germany: Wiley-VCH. 2016. p. 143-182. (Advanced Biotechnology). https://doi.org/10.1002/9783527697441.ch06