Genome analysis of Ranavirus frog virus 3 isolated from American Bullfrog (Lithobates catesbeianus) in South America

Marcelo Candido*, Loiane Sampaio Tavares, Anna Luiza Farias Alencar, Cláudia Maris Ferreira, Sabrina Ribeiro de Almeida Queiroz, Andrezza Maria Fernandes, Ricardo Luiz Moro de Sousa

*Corresponding author for this work

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    Abstract

    Ranaviruses (family Iridoviridae) cause important diseases in cold-blooded vertebrates. In addition, some occurrences indicate that, in this genus, the same virus can infect animals from different taxonomic groups. A strain isolated from a Ranavirus outbreak (2012) in the state of Sao Paulo, Brazil, had its genome sequenced and presented 99.26% and 36.85% identity with samples of Frog virus 3 (FV3) and Singapore grouper iridovirus (SGIV) ranaviruses, respectively. Eight potential recombination events among the analyzed sample and reference FV3 samples were identified, including a recombination with Bohle iridovirus (BIV) sample from Oceania. The analyzed sample presented several rearrangements compared to FV3 reference samples from North America and European continent. We report for the first time the complete genome of Ranavirus FV3 isolated from South America, these results contribute to a greater knowledge related to evolutionary events of potentially lethal infectious agent for cold-blooded animals.
    Original languageEnglish
    Article number17135
    JournalScientific Reports
    Volume9
    Number of pages7
    ISSN2045-2322
    DOIs
    Publication statusPublished - 2019

    Cite this

    Candido, M., Tavares, L. S., Farias Alencar, A. L., Ferreira, C. M., Queiroz, S. R. D. A., Fernandes, A. M., & Sousa, R. L. M. D. (2019). Genome analysis of Ranavirus frog virus 3 isolated from American Bullfrog (Lithobates catesbeianus) in South America. Scientific Reports, 9, [17135]. https://doi.org/10.1038/s41598-019-53626-z