Genome analysis of Ranavirus frog virus 3 isolated from American Bullfrog (Lithobates catesbeianus) in South America

Marcelo Candido; Loiane Sampaio Tavares; Anna Luiza Farias Alencar; Cláudia Maris Ferreira; Sabrina Ribeiro de Almeida Queiroz; Andrezza Maria Fernandes; Ricardo Luiz Moro de Sousa

doi:10.1038/s41598-019-53626-z

Genome analysis of Ranavirus frog virus 3 isolated from American Bullfrog (Lithobates catesbeianus) in South America

Marcelo Candido^*, Loiane Sampaio Tavares, Anna Luiza Farias Alencar, Cláudia Maris Ferreira, Sabrina Ribeiro de Almeida Queiroz, Andrezza Maria Fernandes, Ricardo Luiz Moro de Sousa

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

Ranaviruses (family Iridoviridae) cause important diseases in cold-blooded vertebrates. In addition, some occurrences indicate that, in this genus, the same virus can infect animals from different taxonomic groups. A strain isolated from a Ranavirus outbreak (2012) in the state of Sao Paulo, Brazil, had its genome sequenced and presented 99.26% and 36.85% identity with samples of Frog virus 3 (FV3) and Singapore grouper iridovirus (SGIV) ranaviruses, respectively. Eight potential recombination events among the analyzed sample and reference FV3 samples were identified, including a recombination with Bohle iridovirus (BIV) sample from Oceania. The analyzed sample presented several rearrangements compared to FV3 reference samples from North America and European continent. We report for the first time the complete genome of Ranavirus FV3 isolated from South America, these results contribute to a greater knowledge related to evolutionary events of potentially lethal infectious agent for cold-blooded animals.

Original language	English
Article number	17135
Journal	Scientific Reports
Volume	9
Number of pages	7
ISSN	2045-2322
DOIs	https://doi.org/10.1038/s41598-019-53626-z
Publication status	Published - 2019

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Candido, M., Tavares, L. S., Farias Alencar, A. L., Ferreira, C. M., Queiroz, S. R. D. A., Fernandes, A. M., & Sousa, R. L. M. D. (2019). Genome analysis of Ranavirus frog virus 3 isolated from American Bullfrog (Lithobates catesbeianus) in South America. Scientific Reports, 9, [17135]. https://doi.org/10.1038/s41598-019-53626-z

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title = "Genome analysis of Ranavirus frog virus 3 isolated from American Bullfrog (Lithobates catesbeianus) in South America",

abstract = "Ranaviruses (family Iridoviridae) cause important diseases in cold-blooded vertebrates. In addition, some occurrences indicate that, in this genus, the same virus can infect animals from different taxonomic groups. A strain isolated from a Ranavirus outbreak (2012) in the state of Sao Paulo, Brazil, had its genome sequenced and presented 99.26% and 36.85% identity with samples of Frog virus 3 (FV3) and Singapore grouper iridovirus (SGIV) ranaviruses, respectively. Eight potential recombination events among the analyzed sample and reference FV3 samples were identified, including a recombination with Bohle iridovirus (BIV) sample from Oceania. The analyzed sample presented several rearrangements compared to FV3 reference samples from North America and European continent. We report for the first time the complete genome of Ranavirus FV3 isolated from South America, these results contribute to a greater knowledge related to evolutionary events of potentially lethal infectious agent for cold-blooded animals.",

author = "Marcelo Candido and Tavares, {Loiane Sampaio} and {Farias Alencar}, {Anna Luiza} and Ferreira, {Cl{\'a}udia Maris} and Queiroz, {Sabrina Ribeiro de Almeida} and Fernandes, {Andrezza Maria} and Sousa, {Ricardo Luiz Moro de}",

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Genome analysis of Ranavirus frog virus 3 isolated from American Bullfrog (Lithobates catesbeianus) in South America. / Candido, Marcelo; Tavares, Loiane Sampaio; Farias Alencar, Anna Luiza; Ferreira, Cláudia Maris; Queiroz, Sabrina Ribeiro de Almeida; Fernandes, Andrezza Maria; Sousa, Ricardo Luiz Moro de.

In: Scientific Reports, Vol. 9, 17135, 2019.

Research output: Contribution to journal › Journal article › Research › peer-review

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AU - Candido, Marcelo

AU - Tavares, Loiane Sampaio

AU - Farias Alencar, Anna Luiza

AU - Ferreira, Cláudia Maris

AU - Queiroz, Sabrina Ribeiro de Almeida

AU - Fernandes, Andrezza Maria

AU - Sousa, Ricardo Luiz Moro de

PY - 2019

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N2 - Ranaviruses (family Iridoviridae) cause important diseases in cold-blooded vertebrates. In addition, some occurrences indicate that, in this genus, the same virus can infect animals from different taxonomic groups. A strain isolated from a Ranavirus outbreak (2012) in the state of Sao Paulo, Brazil, had its genome sequenced and presented 99.26% and 36.85% identity with samples of Frog virus 3 (FV3) and Singapore grouper iridovirus (SGIV) ranaviruses, respectively. Eight potential recombination events among the analyzed sample and reference FV3 samples were identified, including a recombination with Bohle iridovirus (BIV) sample from Oceania. The analyzed sample presented several rearrangements compared to FV3 reference samples from North America and European continent. We report for the first time the complete genome of Ranavirus FV3 isolated from South America, these results contribute to a greater knowledge related to evolutionary events of potentially lethal infectious agent for cold-blooded animals.

AB - Ranaviruses (family Iridoviridae) cause important diseases in cold-blooded vertebrates. In addition, some occurrences indicate that, in this genus, the same virus can infect animals from different taxonomic groups. A strain isolated from a Ranavirus outbreak (2012) in the state of Sao Paulo, Brazil, had its genome sequenced and presented 99.26% and 36.85% identity with samples of Frog virus 3 (FV3) and Singapore grouper iridovirus (SGIV) ranaviruses, respectively. Eight potential recombination events among the analyzed sample and reference FV3 samples were identified, including a recombination with Bohle iridovirus (BIV) sample from Oceania. The analyzed sample presented several rearrangements compared to FV3 reference samples from North America and European continent. We report for the first time the complete genome of Ranavirus FV3 isolated from South America, these results contribute to a greater knowledge related to evolutionary events of potentially lethal infectious agent for cold-blooded animals.

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